G+ STAPHYLOCOCCI Flashcards
general characteristics of Staph. spp.
gram + cocci in cluster
catalase +
normal inhabitants of skin/mucus membrane
golden yellow pigment of S. aureus
lipochrome
due to carotenoid
found in cell wall of S. aureus that neutralizes IgG
protein A
virulence marker of S. aureus
coagulase
enzyme of S. aureus that digests clot
staphylokinase
enterotoxins associated with staph food poisoning
enterotoxin A, B, D
enterotoxins associated with toxic shock syndrome
enterotoxin B, C
enterotoxins associated with staphylococcal pseudomembranous enterocolitis
enterotoxin B
causes menstruating-associated TSS
toxic shock syndrome toxin 1
causes ritter disease/bullous impetigo
exfoliative/epidermolytic toxin
exfoliative toxin A, B
cytolytic toxins:
lyses rbcs
causes severe tissue damage
α-hemolysin
cytolytic toxins:
acts on the sphingomyelin
aka hot-cold lysin
β-hemolysin
cytolytic toxins:
associated with panton valentine leukocidin
γ-hemolysin
cytolytic toxins:
less toxic
δ-hemolysin
exotoxin that is lethal to pmn cells
associated with community acquired MRSA
panton valentine leukocidin
coagulase -
most common cause of nosocomial uti
S. epidermidis
sensitive to novobiocin
>16 mm
S. epidermidis
resistant to novobiocin
<16 mm
S. saprophyticus
coagulase -
causes acute uti in young women
S. saprophyticus
coagulase - but with clumping factor
can mimic S. aureus infections
contains mecA gene
S. lugdunensis
primary plate for Staph spp.
BAP (SBA)
differential
MSA
S. aureus can ferment mannitol
special media for isolation of MRSA
chromagar staph aureus
test used to differentiate S. aureus from other Staph spp.
coagulase test
