fungus Flashcards

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1
Q

primarily pathogenic

A

dimorphic histoplasma capsulatum

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2
Q

fungi cause

A

mycoses
mycotoxicosis
hypersensitivity

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3
Q

aflatoxicosis

A

aspergillus

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4
Q

ergotism

A

mycotoxicosis by claviceps purpura

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5
Q

hypersensitivity i, iii

A

aspergillus fumigatus - bronchopulmonary aspergillosis

allergic rhinosinusitis

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6
Q

wet mounts

A

KOH - alkali digest tissue

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7
Q

Calcofluorwhite

A

binds to cellulose and chitin

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8
Q

gram stains

A

yeast, yeast like

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9
Q

india ink

A

negative staining of capsulated cryptococcus

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10
Q

Methamine silver, per iodic acid Schiff

A

stain for fungi

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11
Q

LCB

A

fungal colonies

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12
Q

culture

A

media with low pH
aerobic
25-30°C

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13
Q

media

A

sabouraud dextrose agr
sabouraud glucose neopeptone agar
pH 4.5
antibacterial

bloog agar, BHI agar/broth

czapek dox, bird seed, corn meal media

cycloheximide- inhibit contaminant mould

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14
Q

culture

A

slide culture, cellophane tape mount

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15
Q

serology

A

antibody
antigen
immunohistochemistry
skin test - type iv fr histoplasma and coccidiodes

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16
Q

latex agglutination

A

antigen detection of cryptococcus capsule, candida, aspergillus

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17
Q

polyenes

A

binds to sterols- disrupt cell membrane

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18
Q

imidazole, triazole

A

inhibit ergosterol synthesis

19
Q

pyrimidine

A

inhibits dna rna synthesis

20
Q

grisans

A

inhibits microtubules assembly

21
Q

caspofungin, micafungin

A

inhibits beta glucan synthesis in cell wall

22
Q

tinea versicolour

A

superficial mycoses

23
Q

tinea Nigra

A

superficial mycoses

24
Q

tinea pedra

A

superficial mycoses

25
Q

dermatophytes

A

cutaneous infection
cornified skin layer + its appendages
inflammation, allergy

26
Q

candida albicans

A

systemic and deep mycoses

27
Q

malassezia furfur yeast like fungus

A

tinea versicolour - stratum corneum
macular depigmentation
superficial mycoses
SDA with olive oil

28
Q

exophiala werneckii

A

tinea nigra - corneum, brown pigmentation

SDA - grey black colonies

29
Q

piedra

A

firm irregular nodules
black and white piedra

caused by P hortae, Trichosporon

30
Q

keratinophilic hyaline filamentous dermatophytes - microsporum, trichophyton, epidermophyton

A

cause tinea- barbae, glabrosa, imbricata, (scaly papulosquamous patches), capitis (favus, kerion), cruris, epdis,manuum, ungunium

31
Q

dermatophytosis features

A

red, itchy, scaly, circular, dry lesions
flavus- crusty scaring of hair - alopecia
kerion- boggy inflammatory scalp lrsion
nail friable, debris under it

hyphae and athrospores in the lesion
dermatophytids - sterile vesicular hypersensitivity lesion

32
Q

Woods lamp test

A

green yellow - microsporum

golden yellow - malassezia

33
Q

fungal hair infection

A

ectothrix

endothrix

34
Q

hair perforation test

A

t. mentagrophye - wedge in hair

t rubrum - don’t

35
Q

trichophyton colonies

A

rubrum

powdery, waxy, velvety
PIGMENTATION varies
microconidia - in clusters along hyphae/on conidiophores
macroconidia- less, thin elongated distinctive
hyphae- raquet mycelium, spiral, favic
SKIN, HAIR, NAILS

36
Q

Microsporum

A

cotton like colnies, brown white
macroconidia single at hyphae tip
hair, skin

37
Q

epidermophytes

A

greenish powdery
macroconidia, pear clusters
skina nd nail infection

38
Q

T rubrum

A

dermatophytes

39
Q

E floccosum

A

dermatophytes

40
Q

M audouinii

A

dermatophytes

41
Q

t verrucsum

A

dermatophytes- c

42
Q

m canis

A

dermatophytes

43
Q

carcinoid heart disease

A

bioactive substances from carcinoid tumor like serotonin

44
Q

patent ductus arteriosus

A

PG E2