Fungi and Parasites Flashcards

1
Q

What organisms can cause tinea capitis, corporis, curis, pedis, manum, ungium?

A

Microsporum, Trichophyton, Epidermophyton

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2
Q

Malassezia furfur causes? S/S?

A

Pityriasis versicolur - meatballs and spaghetti appearance on KOH prepared skin scrapings

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3
Q

What can you tell me about Candida Albicans?

A

Dimorphic, cold is mould, warm is yeast and can cause oral or vaginal thrust (thick, white, cheesey discharge)

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4
Q

What can Rose gardeners pick up? S/S?

A

Sporothrix schenckii

Bumps along lymph channels in leg or forearm

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5
Q

Madurella grisea causes?

A

Chronic infxn of food, swollen, draining sinuses

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6
Q

Fungi grow best in what medium?

A

Sabouraud

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7
Q

Black nodules on hair?!! You suspect this fungus to be at fault!

A

Piedra hortae

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8
Q

White or beige nodules on your hair? You picked up what fungus?

A

Trichosporum Beigelli

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9
Q

What do you suspect to cause warty lesions on woodcutter’s feet? (Madura foot)

A

Madurella mycetomatis or grisea

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10
Q

Ohio valley fever (mississippi too) is caused by? Spread by? Causes?

A

Histoplasma cpsulatum
Inhalation of spores, bat or chicken droppings
Asymptomatic in immunocompetent ppl and hide in macrophages but can affect lung, spleen, liver, adrenals

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11
Q

San Joaquin Valley fever is caused by? Spread by? S/S?

A

Coccidioidtes Immitis
Inhalation of spores (SW US deserts)
Lung infxn,joint pain, erythema nodusum (legs)

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12
Q

North American Blastomycosis is caused by? Transmitted through? SS?

A

Blasomyces dermatidis, East coast US
Inhalation of spores
Skin, bone, lung infxn

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13
Q

South American Blastomycosis is caused by? Transmitted through? SS?

A

Paracoccidioides brasiiensis
inhalation of spores (latin america)
Mouth and nose ulcerations

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14
Q

Which opportunistic fungi affect HIV/AIDS patients?

A

Aspergillus fumigatus (hemoptysis), cryptococcus neoformans (meningitis, brain abscess, pneumonia), candida albicns (thrush), pneumocystis jiroveci (ground glass pneumonia)

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15
Q

What causes Chagas disease and what is the vector? S/S?

A

Trypanosoma Cruzi
Reduviid sand fly bite
Dysphagia, heart failure (mega esophagus, dilated cardiomegaly)

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16
Q

What causes sleeping sickness and what is the vector?

A

Trypanosoma Gambiense

Tetse fly bite

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17
Q

A phlebotomous sandly bite can transmit what parasites? S/S?

A

Leishmania donovania - kala azar hepatosplenomegaly

Leishmania Brasilliensis - espundia mucocutaneous ulcerations

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18
Q

What tapeworm can you get from:
Pork?
Beef?
Dog feces?

A

Taenia solium
Taenia saginata
Echinococcus granulosus

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19
Q

What is the largest fish tapeworm?

Smallest tapeworm?

A

Diphyllobothrium latum

Hymenolepis nana

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20
Q

What causes River blindness disease and what is the vector?

A

Onchocera volvulus

Simulium blackfly bite

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21
Q

What parasite causes elephantiasis disease and what is the vector?

A

Wuchereria bancrofti

Aedes aegypti mosquito

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22
Q

What causes eye worm disease and what is the vector?

A

Loa loa

Chrysops fly bite

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23
Q

Types of protozoa?

A

Ameba
Flagellata
Ciliate
Sporozoa

24
Q

Amebic dysentery parasite? S/S?

A

Entameba histolytica

Stool w/flecks of blood and mucous (liver abscess)

25
How is trypanosoma cruzi spread?
Kissing
26
What sporozoa infxn is spread from infected cat feces? S/S?
Toxoplasma gondii | X placenta --> miscarriage, chorioretinitis, intracranial calcification
27
Let's talk about plasmodium malaria... spread by? Plasmodium falciparum S/S? Blackwater fever cause?
Female aneopheles mosquitoes (injects sporozites which become merozoites in liver and then trophozoites to gametocytes) Daily cycles of ever, cerebral infection convulsion death Excessive hemoglobin in the urine
28
MC intestinal nematode in US? Tests? S/S?
Enterobius vermicularis/pinworms Scotch tape test Perianal itching
29
2nd MC intestinal nematode in US? S/S?
Ascaris lumbricoides/roundworms | Intestinal and common bile duct obtruction
30
Strongyloides stercoralis are? S/S?
Threadworms | Perianal itching at night
31
Whipworms are known as? S/S?
Trichuris trichuria | Weight loss, ab pain, bloody diarrhea, rectal prolapse
32
Trichinella spiralis is? S/S?
Pork roundworm - trichinosis | fever, uscle pain, periorbital edema
33
MC hookworm in US? S/S?
Necatoramericanus | Iron deficiencyanemia
34
Simulium blackfly transmits? Disease? S/S?
Onochocera volvulus River blindness Hyperpigemented skin
35
Elephantiasis is caused by? S/S? Vector?
Wuchereria bancrofti Filariasis, chronic lymph blockage Culex filiariasis
36
Chrysops biting fly transmits Disease?
Loa loa | Eye worm disease
37
Largest fish tapeworm? S/S?
Diphyloobothrium latum | Vit B12 deficiency
38
Hymenolepis nana is? S/S?
Smallest tapeworm in eggs/cereal | Diarrhea, ab pain, weight loss
39
What worm do you get from undercooked pork? beef?
Taenia solium | Taenia saginata
40
Accidental contact with contaminated dog feces is sheep-raising areas can give you? S/S?
Echinoccougranulosus | Hydatid cysts in the liver causing hepatomegaly or cysts in lungs
41
How are Schistosoma species spread? ` Hematobium egg? Area? S/S? Japnicum? Mansoni?
Female worm in split in male worm snails are intermediate hosts cause bilharziaiasis Hematobium: egg w/terminal spine in urine, Africa and Middle East, affects bladder - hematuria and squamous cell bladder cancer Japonicum: egg w/rudimentary spine found in stool, Asia, affects gut and liver Mansoni: Egg with a lateral spine in stool, liver cirrhosis, portal hypertension, swimmer's itch (in ducks in Costal New Jersey)
42
Clonorchis sinensis is? Where? S/S?
Chinese liver flukes, endemic in far east from undercooked fish Feed on bile in liver, fever tender hepatomegaly, mild jaundice later chronic cholangitis, cholangiocarcinoma
43
Fasciola hepatica is? Where? S/S?
Liver flukes from infected sheep and aquatic snail is intermediate host Diarrhea, ab pain
44
Pragonimus westermani is? Where? S/S?
Lung flukes from undercooked crab/crayfish endemic in Asia, Africa, South America Chronic cough, hemoptysis
45
Name this skin test: | Injection of splenic extra from a pt with sarcoidosis causes a skin reaction (non-caseous granulomas) 4-6 weeks later
Kveim
46
Mantoux/Heaf/Tine test is for? What is injected?
TB | Purified Protein Derivative (from TB bacillus)
47
What are the urea-splitting bacteria?
Klebsiella pneumoniae, proterus mirabilis, ureaplasma, nocardia, cryptococcus neoformans, H. pylori
48
Biological assay that asses mutagenic potential of chemical compounds with strains of Salmonella typhimurium?
Ames test
49
This test is a biochemical rxn in which anticapsular ab bind to bacterial capsule - swell - more visible? Organisms affected?
Quellung rxn | Strep pneumoniae, Klebsiella pneumoniae, hemophilus influenzae, salmonella, N meningitides
50
``` Briefly describe: Case study Case Control Cohort study RCT SR meta-analysis ```
Case study: describe/interpret individual case Case Control: patients who have disease or outcome w/those who don't Cohort study: samples prospectively w/disease or outcome RCT: random assigned to exp or control outcomes compared SR: combines all info RE outcome and summarize finding meta-analysis: combo qualitative data from several studies for higher statistical power
51
Water purification steps?
``` Filtration Flocculation (add aluminum) Sedimentation Sludge digestion (anaerobic bacteria) Sand filatration: remove anaerobic baceria Aeration kill anaerobic bacteria Chlorination ```
52
``` Agencies and what they do FDA? Public health department (PHD) EPA USDA OSHA CDC HSA NIH ```
FDA: quality of drugs, cosmetics, food, ad health products PHD: disease surveillance, restaurant inspection EPA: water/air quality USDA: meat/milk inspection OSHA: workplace safety, hazardous materials CDC: epidemiological research, health stats HSA: oversee health care to underserved NIH: oversee disease research + funding
53
Compare incidence to prevalence | Mortality to morbidity
Incidence: # of NEW cases in population at given time vs Prevalence: # of cases PRESENTLY (new + old) Mortality:: # of people who die from a disease vs morbidity # of ppl who HAVE the disease
54
Endemic? Epidemic? Pandemic?
End: normal Epi: sudden increase (local) Pan: sudden rise (worldwide)
55
Emerging diseases (not COVID)
Ebola, lassa fever, lyme, HIV/AIDS, hantavirus, SARS, H1N1, MERS
56
Re-emerging diseases?
Multi-drug resistant TB | Methicillin resistant staphylococcus aureus