Fungi Flashcards
Fungi Classifications (4)
- Zygomycetes
- Ascomycetes
- Basidiomycetes
- Fungi Imperfecti
Zygomycetes
forms sporangium where many nuclei undergo meiosis (ballsack, z=biggest)
Ascomycetes
forms ascus (4-8 spores in sac- long narrow dick)
Basidiomycetes
spores (conidia) bud from basidium- club-shaped terminal cell (baseball bat)
Distinguishing fungi by color (2)
Dermaticious (color) vs. hyaline (colorless)
Growth forms (8)
- Yeast
- Mold
- pseudohyphae
- Clamydospores
- Conidia
- Macroconidia
- Arthroconidia
- Phiaoloconidia
Yeast
Smooth, creamy round in culture (ex candida)
Mold
Filaments/hyphae, form mycelium, (ex aspergillus)
-form fuzzy,colored colonies
Pseudohyphae
fungi growth form where yeast buds elongate but dont separate- looks similar to hyphae but individual cells
Chlamydospores
Large round terminal cells with thick walls
Conidia
Thick walled dispersion stage, microconidia are tiny ones
Macroconidia
Giant conidia, septa walls divide
Arthroconidia
Form chain of cells, every other has thick septa dividing, later break along these joints
Phiaoloconidia
Dominatrix Randy Trident- conidia chains bud from terminal cells
Types of fungal infections
superficial, cutaneous, subcutaneous, systemic
-primary vs. opportunists
Piedra
Superficial fungal infection of hair
Tinea (disease, hallmark, exs)
superficial infection of skin
- see lesion with inflamed ring, cleared center
- exs: trichophyton, epidermophyton, microsporum
- distinguish by micro/macroconidia, but usually dont ID (just give drug and kill)
Tinea Corporis
ringworm (tinea on body surface, mainly arms/legs)
Tinea Capitis (disease, hallmark)
Tinea of head
-Use fluorescent Wood’s Lamp to ID
Tinea barbae
Tinea of face
Tinea pedis
Athlete’s foot
Tinea unguim
aka onychomycosis (fingernail infection)
Subcutaneous mycoses
Usually infected by trauma, fungi enter. Form abcess, or mycotoma (fungus tumor)
Sporothrix Schenkii (disease, common infection, appearance)
- cause of subcutaneous mycosis
- found in soil, common infection among gardeners, stick with wood
- elongated yeast
- looks similar to actinomycetes (bacteria) so need distinguish before treatment
Systemic mycoses (hallmark, mode of infection, human/human transmission?, form)
endemic to specific area, infect healthy people
- usually respiratory infection first
- occupational hazard
- little human/human transmission
- Dimorphic (yeast at 37º in infection, hyphae in culture at 30º)
Blastomyces Dermatitis (infection type, form, geography)
Systemic mycosis
- visualize with KOH
- broad-based buds (BBB for BD)
- found east of mississippi in river banks, beaver dams
Histoplasma Capsulatum (culture/tissue appearances, geography, infection)
- systemic mycoses
- “Black sun” appearance in culture, tiny intracellular yeast in infection(often of macrophages)
- Ohio/Mississippi river valleys, bird/bat guano soil
Coccidioides immitis (geography, form in culture/tissue)
Southwest US desert soil
-large spherule in lung, arthroconidia in culture
Paracoccidiodes Braziliensis (form, geography)
“ships wheel”- yeast with buds
-found in central/south america
Candida Albicans (form, infection location, infections)
- tons of morphologies
- normal flora of mucous membranes (skin, GI, vagina)
- can cause vaginal infections (no colored discharge like trachomatosis), GI/skin infections in infants, thrush in adults
- kind of opportunist, so thrush can be sign of immune deficiency
Cryptococcus neoformans (form, special stain, infection)
Heavily encapsulated yeast, visualize with india ink
-infects brain/meninges
(so commonly confused with s. pneumoniae, h. influenzae, n. meningitides)
Opportunistic Pathogens (4)
- Aspergillus
- Zygomycetes (mucor + rhizopus)
- pneumocystis jirovecii
- Candida kind of
Aspergillus (infection demographic, body area, form)
- Opportunistic fungus common in neutropenic patients
- lung infection, can spread to heart/vessels
- form hyphae in tissue
Mucor + Rhizopus (infection, location)
Opportunistic fungi that infect nasopharynx, can spread to brain
Pneumocystis Jirovecii (infection, patient demographic)
Opportunistic fungi
-Rare cause of disease- common in AIDS patients