Fungal Pathogens

Question 1

What type of environment favors most fungi?

Answer 1

aerobic

Question 2

What types of cells are fungi?

Answer 2

eukaryotes

Question 3

What is the fungal cell wall composed of?

Answer 3

beta glucans

Question 4

What is the role of beta glucans for a host?

Answer 4

initiates an immune response

Question 5

What is the structural component of cell walls?

Answer 5

chitin

Question 6

What type of linkages are common in linkages?

Answer 6

N-acetylglucosamine chain (1,4)

Question 7

How many glucan synthases are there?

Answer 7

1

Question 8

What is the fungi equivalent of cholesterol?

Answer 8

ergosterol

Question 9

What are the two fungal morphologies?

Answer 9

yeast and filamentous

Question 10

What are dimorphic fungi?

Answer 10

hyphae at ambient temperature and yeast at 37 C

Question 11

Describe hyphae?

Answer 11

filamentous apical growth

Question 12

What is difference in hyaline and dematiaceous?

Answer 12

light vs dark

Question 13

What is a network of filaments?

Answer 13

mycelium

Question 14

When aare infective propagules generally made?

Answer 14

asexual reproduction

Question 15

What is the anamorphic stage?

Answer 15

asexual reproduction

Question 16

What are the two types of infective particles?

Answer 16

conidia and spores

Question 17

What are the three types of vegetative asexual reproduction?

Answer 17

blastoconidia, chlamydoconidia, and arthroconidia

Question 18

What are blastoconidia?

Answer 18

yeasts, bud growth, clusters

Question 19

What are chlamydoconidia?

Answer 19

thick walled, terminal

Question 20

What are arthroconidia?

Answer 20

barrel shaped, segment of hyphae

Question 21

What type of hyphae do conidiophores have?

Answer 21

septate

Question 22

What type of hyphae do sporangiospores have?

Answer 22

aseptate

Question 23

What are the types of sexual reproduction?

Answer 23

mucormycotina, ascomycota, and basidomycota

Question 24

Describe mucormycotina?

Answer 24

aseptate hyphae and fast growing

Question 25

Describe ascomycota?

Answer 25

septate hyphae (aspergillus, candida, histoplasma)

Question 26

What do polyenes do?

Answer 26

bind to ergosterol to form pores

Question 27

What do azoles do?

Answer 27

inhibit fungal enzymes to block ergosterol synthesis

Question 28

What do allylamines do?

Answer 28

inhibit fungal enzymes to inhibit ergosterol synthesis

Question 29

What do echinocandins do?

Answer 29

inhibits activity of B 1,3 glucan synthase

Question 30

What root is seen in echinocandins?

Answer 30

-fungins

Question 31

What does flucytosine do?

Answer 31

inhibits fungal DNA and RNA synthesis