Fungal Meningitis Flashcards
Cryptococcosis MC occurs in what population
HIV-infected
When I say cryptococcus, you say ____?
Pigeon
T/F – Cryptococcus is dimorphic
False
T/F – Cryptococcus is encapsulated
True; key for virulence b/c antiphagocytic
T/F – Cryptococcus is a yeast
True
T/F – Initial infection by cryptococcus is symptomatic
False
How do you dx cryptococcus? Which is more sensitive method?
LP – Stain CSF w/ India ink and look for halos, CSF test for antigens; test for antigens
Rx for cryptococcus?
Amphotericin B and Flucytosine
Causal organism in steroid-assoc. meningitis?
Exserohilum rostratum
How to dx SAM?
CSF analysis – culture
Rx for steroid-assoc. meningitis? What if first-line Rx fails?
IV voriconazole; Amphotericin B