Bacterial Meningitis -- H. Influenzae Flashcards
1
Q
Most important serotype?
A
B
2
Q
Chief virulence factor?
A
Capsule
3
Q
Why is immunity short-lived?
A
Polysaccharide antigens –> T-cell independent
4
Q
What is the structure of the Hib vaccine?
A
Polyribosylribitol phosphate (PRP) conjugated to carrier protein (Diphtheria toxoid)
5
Q
When is Hib vaccine given?
A
2-15 months