fungal infections Flashcards
what are fungi
eukaryotic organisms they differ from both plants and animals, therefore belong to their own kingdom, fungi exist in two forms
immunity to fungal infection
innate immune system
mucosal surfaces
epithelial surfaces
body temperature
candida albicans- yeast mucosal candida
pathogencity- hyphal switch,environmental
change in PH, flora, temperature, breakdown in barrier
vaginal candidiasis- antibiotics kill lactobacilli which increases PH inducing hyphal switch and invasion
treatment for candida albicans
topical treatment nystatin
azoles- flucomazole inhibit fungal cell membrane synthesis
specific to cell wall of fungi
moulds superficial dermatophyte infections mould
most prevalent fungal infection
pathogenecity spores land on skin and nail
utilise keratin as a nutrient source
trichophyton
dimorphic fungal infections
blastomyces soil that contains organic debris
coccidiodes immits
