Fungal Flashcards
1
Q
Candida albicans
A
Cell wal ligands: agglutinin-like (AL) and hyphal wall protein (Hwp), biofilm, hydrolytic aspartyl proteinase
2
Q
Aspergillus
A
Proteases, gliotoxin, fumagillin, verruculogen, helvolic acid to slow ciliary beat in respiratory tract, B-glucans to block ROS
3
Q
Coccidioides immitis
A
Spherule too large for phagocytosis; arginase I and coccidioidal urease
4
Q
Blastomyces
A
Blastomyces adhesion factor 1 (BAD1) to bind to alveolar macs
5
Q
Cryptococcus
A
Melanin
Glucosylceramide synthase to survive in mucosa
Glucuronoxylomannan in capsule to inhibit phagocytosis
6
Q
Angioinvasive Aspergillosis
A
Melanin, mannitol, catalase, SOD