Functions Of The Brain Flashcards
What pathway for visual perception and what lobe is involved
Anterior Visual Pathway, occipital lobe
Three streams in visual perception
Dorsal- Fast, Parietal
Anterior- Fast, PFC and limbic structures
Ventral- Slow, energy intensive , temporal
Dysfunction of attention key sign in what disease
Delirium
Three main types of memory
Working
Long term
Sensory
Where are:
Central executive
ACC / attention controller
Episodic buffer
Phonological loop
Visuo-spatial sketch pad
PFC
Frontal
Parietal
Frontal to temporal
Occipital
What forms long term memory and problem if damaged
Hippocampus, anterograde amnesia
limbic system structures (for reward and negative emotion)
Positive- nucleus accumbens, medial forebrain bundle, ventral tegmental area
Negative- Amygdala
What are the 4 dopamine pathwats
Mesocortical-reward, cognition
Mesolimbic, reward, emotion
Nigrostriatal- iPD
Tubuloinfundibular- prolactin production
What structures in mesolimbic and mesocortical pathway release dopamine
Substantia Nigra and VTA
Two kinds of apraxia and what lobes are involved
Executive- deficit in sequencing complex movements( SMA and PMA)
Posterior - deficit in spatial construction of complex movements (PPC)
What is involved in CST
Motor regions of cerebral cortex
Brainstem
Spinal cord
Weakness in CST pathology - which muscles
Biceps and quadriceps
What is involved in basal ganglia loop
Cortex
Basal ganglia
Thalamus
Lead pipe Vs clasp knife
Hypokinetic movement disorder( rigidity) Vs spasticity in Pyramidal tract disorder
Where is dopamine supplied from and where to
From Substantia nigra in midbrain to basal ganglia (striatum in particular)
What protein accumulates in Parkinson’s
Alpha synuclein
Symptoms of Parkinson’s
Bradykinesia
Rigidity
Tremor
Postural instability
Treatment for Parkinson’s and what must it be given with
Levo- DOPA with DOPA decarboxylase inhibitor eg. carbidopa or benserazide ( so dopamine is only converted in CNS)
Is tremor EP or pyramidal
Extra pyramidal- normal reflexes and no weakness
What kind of tremor in Parkinson’s
Tremor at rest (even when body part is fully supported against gravity)
Essential tremor caused by?
Alcohol intoxication
Can be postural (against gravity) or simple kinetic(during entire movement trajectory)