Functions of CD markers

Question 1

Function of CD2

Answer 1

Adhesion molecule

Question 2

Function of CD3

Answer 2

Signal transduction by the TCR

Question 3

Function of CD4

Answer 3

Co-receptor for TC-MHC II interaction

Question 4

Function of CD8

Answer 4

Co-receptor for MHC class -restricted T cells

Question 5

Function of CD14

Answer 5

Bind LPS

Question 6

Function of CD16

Answer 6

Opsonization ADCC

Question 7

Function of CD18

Answer 7

Cell adhesion molecule

Question 8

Function of CD19

Answer 8

Coreceptor with CD21 for B-cell activation (signal transduction

Question 9

Function of CD20

Answer 9

Unknown role in B-cell activation

Question 10

Functions of CD21

Answer 10

Receptor for complement fragment C3d

Forms co-receptor complex with CD19

Question 11

Function of CD25

Answer 11

Alpha chain of IL-2 receptor

Question 12

Function of CD28

Answer 12

T-cell receptor for co-stimulatory molecule B7

Question 13

Function of CD34

Answer 13

Cell-cell adhesion, binds L-selectin

Question 14

Functions of CD40

Answer 14

Binds CD40L
Role in T-cell dependent B cell macrophage
Dendritic cell and endothelial cell activation

Question 15

Function of CD56

Answer 15

Cell Adhesion

Question 16

Function of CD152 (CTLA-4)

Answer 16

Negative regulation” competes with CD28 for B7 binding