functional GI disorders

Question 1

What sx’s would be defined as functional dyspepsia under the Rome criteria IV (3)

Answer 1

Postprandial fullness, early satiety, epigastric pain

Question 2

What happens in duodenal alterations

Answer 2

Once you get alterations, you get mucosal barrier dysfunction which results in inflammation, altered enteric nerve function (gut/brain relo), and altered motor dysfunction

Question 3

What alters, due to gut/brain axis dysfunction and what does it lead to?

Answer 3

Alterations in bile acid pool, which leads to inflammation