Fructose can enter Glycolysis

Question 1

Frutokinase

Answer 1

Fructose is phosphorylyated to fructose 1-phosphate by the action of a specific ATP dependent fructokinase.

Question 2

Fructose 1-phosphate aldolase

Answer 2

Catalyzes the clevage of fructose 1-phosphate to dihydroxyacetone phosphate and glyceraldehyde

Question 3

Triose Kinase

Answer 3

The glyceraldehyde is then phosphorylated to glyceraldehyde 3-phosphate, consuming a second molecule of ATP. Dihydroxyacetone phosphate is converted to a second molecule of glyceraldehyde 3-phosphate by the action of triose phosphate isomerase.

Question 4

Yield

Answer 4

The two molecules of glyceraldehyde 3-phosphate produced can then be metabolized to pyruvate by the remaining steps in glycolysis. Metabolizing one mole of fructose to two pyruvate produces two molecules of ATP and two molecules of NADH. This is the same yield as the conversion of glucose to pyruvate.