Fronto Temporal Dementia

Question 1

Px

Insidious onset

Answer 1

Altered character.
Declined or impaired regulation of social conduct.
Emotional blunting.
Impaired insight.
Diet changes.
Perseverative behav.
Cognitive eg reduced attention, retrieval, org, accuracy, self monit.
Neuro- parkinsoism, primit reflexes, MND signs.
Alt speech.

Question 2

Subtypes

Answer 2

Disinhibited
Apathetic
Stereotypic
Notes from ward round- is a syndrome.
-behavioural variant- apathetic or manic (disnihib, fixation)
-speech variant- non fluent aphasia.
-somantic- speak but not unsertand meaning.

Question 3

Pathology

Answer 3

• frontal and ant temporal atrophy. Striatum degen.

- 3 microscopic types- macrovacuolar, pick, MND.

Question 4

Diffs

Answer 4

Other dementia

Fronto temporal degen

Question 5

Investigation

Answer 5

EEG
MSE
CT and MRI
SPECT
Genetics

Question 6

Mx

Answer 6

Curr no specif tx.
AchEI not work.
SSRI lim benefit.