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Pharmacology > From Jen: Drug reactions by system > Flashcards

From Jen: Drug reactions by system Flashcards

1
Q

CV: atropine-like side effects

A

Tricyclics

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2
Q

CV: coronary vasospasm

A

Cocaine

Sumatriptan

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3
Q

CV: cutaneous flushing

A

Niacin
Calcium channel blockers
Adenosine
Vancomycin

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4
Q

CV: dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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5
Q

CV: Torsades de pointes

A 
Class III (sotalol)
Class IA (quinidine)
Cisapride
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6
Q

Heme: Agranulocytosis

A 
Clozapine
Carbamazepine
Colchicine
Propylthiouracil (PTU)
Methimazole
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7
Q

Heme: aplastic anemia

A 
Chloramphenicol
Benzene
NSAIDs
Propylthiouracil (PTU)
Methimazole
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8
Q

Heme: Direct Coombs-positive hemolytic anemia

A

Methyldopa

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9
Q

Heme: Gray baby syndrome

A

Chloramphenicol

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10
Q

Heme: hemolysis in G6PD deficiency

A 
Isoniazid
Sulfonamides
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin

(IS PAIN)

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11
Q

Heme: megaloblastic anemia

A

Phenytoin
Methotrexate
Sulfa drugs

(have a BLAST with PMS)

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12
Q

Heme: Thrombotic complications

A

OCPs

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13
Q

Resp: cough

A

ACE inhibitors (ARB=no cough)

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14
Q

Resp: pulmonary fibrosis

A

Bleomycin
Busulfan
Amiodarone

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15
Q

GI: Acute cholestatic hepatitis

A

Macrolides

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16
Q

GI: focal to massive hepatic necrosis

A

Halothane
Valproic acid
acetaminophen
Amanita phalloides

17
Q

GI: hepatitis

A

Isoniazid (INH)

18
Q

GI: pseudomembranous colitis

A

Clindamycin

ampicillin

19
Q

Repro/Endo: adrenal insufficiency

A

Glucocorticoid withdrawal

Hypothalamic-Pituitary-Adrenal suppression

20
Q

Repro/Endo: gynecomastia

A 
Spironolactone
Digitalis
Cimetidine
Alcohol
Estrogen
Ketaconazole

(Some Drugs Cause Awesome Knockers)

21
Q

Repro/Endo: hot flashes

A

Tamoxifen

Clomiphene

22
Q

MSK: Gingival hyperplasia

A

Phenytoin

23
Q

MSK: Gout

A

Furosemide

Thiazides

24
Q

MSK: osteoporosis

A

Corticosteroids

Heparin

25
Q

MSK: Photosensitivity

A

Sulfonamides
Amiodarone
Tetracycline

(SAT for a photo)

26
Q

MSK: Rash, Steven-Johnson syndrome

A 
Ethosuximide
Lamotrigine
Carbamazepine
Phenobarbital
Phenytoin
Sulfa drugs
PCN
Allopurinol
27
Q

MSK: SLE-type syndrome

A

Hydralazine
INH
Procainamide
Phenytoin

(HIPP)

28
Q

MSK: Tendonitis, tendon rupture, cartilage damage (kids)

A

Fluoroquinolones

29
Q

Renal:

Fanconi’s syndrome

A

Expired tetracycline

30
Q

Renal:

Interstitial nephritis

A

Methicillin
NSAIDs
Furosemide

31
Q

Renal:

Hemorrhagic cystitis

A

Cyclophosphamide

Ifosfamide (prevent by co-administering mesna)

32
Q

Neuro:

Cinchonism

A

Quinidine

Quinine

33
Q

Neuro:

Parkinson-like syndrome

A

Haloperidol
Chlorpromazine
Reserpine
Metoclopramide

34
Q

Neuro:

Diabetes insipidus

A

Lithium

Demeclocycline

35
Q

Neuro:

Seizures

A

Bupropion
Imipenem/cilastatin
Isoniazid

36
Q

Neuro: Tardive dyskinesia

A

Antipsychotics (esp. typicals)

37
Q

Disulfram-like reaction

A

Metronidazole
Certain cephalosporins
Procarbazine
1st gen sulfanylureas

38
Q

Nephro/Neurotoxicity

A

Polymyxins

39
Q

Nephro/Ototoxicity

A

Aminoglycosides
Vancomycin
Loop diuretics
Cisplatin

Pharmacology (18 decks)

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