from imeng

Question 1

Term Explanation

Tight Junction

Answer 1

Tj are the closely associated areas of two cells whose membranes join together forming a virtually impermeable barrier to fluid. It is a type of junctional complex present only in vertebrates.

Question 2

What is cell coat made of?

Answer 2

Glycoproteins and Glycolipids

Question 3

Which glycoprotein constitutes more than 25 percent of all protein in human body?

Answer 3

Collagen

Question 4

Which type of collagen doesn’t form fibril?

Answer 4

Type IV

Question 5

Which ECM molecule consists of a core protein to which chains of glycosaminoglycans are covalently attached?

Answer 5

Proteoglycan

Question 6

Which ECM molecule consists of two similar, but nonidentical polypeptides joined by a pair of disulfide bonds located near the C-termini?

Answer 6

Fibronectin

Question 7

The degradation of extracellular materials, along with cell-surface proteins, is accomplished by a family of zinc-containing enzymes called ()

Answer 7

Matrix metalloproteinases (MMPs)

Question 8

Which molecule is the most important family of receptors that attach cells to their extracellular microenvironment?

Answer 8

Integrins

Question 9

Gap junctions are composed of entirely of an integral membrane protein called ()

Answer 9

Conexon

Question 10

L-selectin means the selectins present on ()

Answer 10

Leukocyte

Question 11

Cadherins are a large family of glycoproteins that mediate () -dependent cell-cell adhesion and transmit signals from the ECM to the cytoplasm

Answer 11

Ca2+-dependent

Question 12

Which of the following organelle contains ribosomes ()

Answer 12

RER (The rough endoplasmic reticulum)

Question 13

The () is thought to function as sorting station that distinguishes between proteins to be shipped back to the ER and those that are allowed to proceed to the next golgi station

Answer 13

The cis Golgi network (CGN)

Question 14

The most common protein modification mode occurs in Golgi complex is ()

Answer 14

Glycosylation

Question 15

Which vesicle moves materials from ER to golgi complex ()

Answer 15

COP II

Question 16

Lysosomal proteins synthesized on rER carry a signal called ()

Answer 16

Mannose-6-Phosphate

Question 17

For lysosomes the high internal proton concentration is maintained by a _ present in the organelle’s membrane

Answer 17

Proton pump

Question 18

() provides a means for selective and efficient uptake to macromolecules that may be present at low concentrations in extracellular fluid, like hormones, enzymes, protein-bound nutrients

Answer 18

Receptor-mediated endocytosis (RME)

Question 19

In general, nerve cells release neurotransmitters via () pathway

Answer 19

Regulated pathway

Question 20

Microfilaments are composed of the protein ()

Answer 20

Actin

Question 21

Which of the cytoskeleton molecule does not have polarity?

Answer 21

Intermediate filament

Question 22

For the microtubules, the plus end is usually terminated by a row of ()

Answer 22

β-Tubulin subunits

Question 23

Which protein may increase the stability of microtubules and promote their assembly?

Answer 23

MAP II

Question 24

Motor protein () moves along microfilament

Answer 24

Myosin

Question 25

Motor protein kinesins move along ()

Answer 25

Microtubules

Question 26

The centrosome is a type of ()

Answer 26

MTOCs (Microtubule-organizing centers)

Question 27

Which is not correct description about sliding-filament model of muscle contraction _

Answer 27

D. During contraction, the shortening of sarcomere resulted from the shortening of the filaments

Question 28

What are the two main types of cell-cell adhesive junctions ()

Answer 28

A. Adherens junctions and desmosomes

Question 29

Which type of vesicles move materials in a retrograde direction from the ERGIC and Golgi stack backward toward the ER ()

Answer 29

COP I

Question 30

Which organelle is important for the regulated destruction of the cell’s own organelles and their replacement ()

Answer 30

Lysosome

Question 31

Which of the following tubulin is very rare in the cell but plays a key role in nucleation of microtubules ()

Answer 31

γ-Tubulin

Question 32

What are the four distinct families of integral membrane proteins play a major role in mediating cell-cell adhesion?

Answer 32

Selectins, Immunoglobulin superfamily, the Integrin family, Cadherins

Question 33

Please list the organelles that form endomembrane system, and briefly describe their functions

Answer 33

nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, endosomes and the cell membrane

Question 34

ECM

Answer 34

an organized network of ec material presented beyond plasma membrane
structute support integrity

Question 35

MTOC

Answer 35

a variety of specialized structures that, because of their role in initiating microtubule formation, are called MTOC.