Frand

Question 1

form mitotic spindle

Answer 1

microtubules

Question 2

segregation of DNA

Answer 2

microtubules

Question 3

ATP-dependent motor proteins that bind microtubules

Answer 3

kinesin and dynein

Question 4

ATP-dependent motor proteins that bind actin

Answer 4

myosin

Question 5

Tau protein binds and stabilizes

Answer 5

microtubules

Question 6

structural variant of Tau aggregates in amyloid plaques leading to – and compromised vesicular transport in diseased neurons

Answer 6

disintegration of microtubules

Question 7

– localize to nuclear envelope

Answer 7

Lamins IF

Question 8

Kertain IF are characteristic of epithelial cells wherein some localize to –

Answer 8

cell-to-cell junctions

Question 9

mutations in gene encoding lamin affect – and cause HGPS (premature aging)

Answer 9

IF

Question 10

mutations that affect keratin IF cause –

Answer 10

blisters

Question 11

kerating IF localize to cell-to-cell junctions and also accumulate in the – during cornification

Answer 11

cytoplasm

Question 12

kertain IFs anchored to plaques on the membrane of two adjacent cells; these attachments are called –

Answer 12

desomosomes

Question 13

major force generator of cells

Answer 13

actin

Question 14

smallest cytoskeleton filament

Answer 14

actin

Question 15

forms dynamic specialized structures virtually in all cells

Answer 15

actin

Question 16

microvilli, adhesion belt, cell cortex, filopodia, lamellapodium. stress fibers, contractile ring

Answer 16

actin

Question 17

The process by which actin filaments appear to move within cells treadmilling occurs slowly in the absence of –

Answer 17

accessory proteins

Question 18

profilin facilitates addition at the positive end of actin by –

Answer 18

increasing the rate of exchange of ADP for ATP

Question 19

makes it more likely that actin breaks under tension

Answer 19

cofilin (ADF)

Question 20

barbed end of actin

Answer 20

profilin

Question 21

pointed end of actin

Answer 21

cofilin

Question 22

accessory protein that affect the stability and geometry of F actin

Answer 22

fascin

Question 23

fascin – actin filaments

Answer 23

bundles

Question 24

– play a role in the formation of protrusions from the cell surface (filapodia)

Answer 24

actin bundles

Question 25

promote different kinds of actin structures

Answer 25

Rho family GTPases

Question 26

Which part of myosin binds F actin?

Answer 26

head

Question 27

myosin head swings towards – powered by ATP hydrolysis

Answer 27

plus end

Question 28

actomyosin filaments linked together by alpha-actinin and other proteins at regular intervals

Answer 28

stress fibers

Question 29

stress fibers are often mechanically couples to – and participate in the exchange of forces between cells and matrices

Answer 29

cell-ECM attachments

Question 30

actomyosin filaments (stress fibers) within cells and protrusions play a key role in –

Answer 30

cell migration

Question 31

parallel rows of aligned – comprise sacromeres within myofibrils

Answer 31

actomyosin filaments (stress fibers)

Question 32

interstitial matrices contain –

Answer 32

ECM molecules and cells

Question 33

– are situated beneath polarized cells

Answer 33

basement membranes

Question 34

– are situated between polarized cells and external environment or its topological equivalent

Answer 34

apical (luminal) matrices