Fractures & Bone Conditions Flashcards
Bone formation
Osteoblasts
Matured Osteoblasts
Osteocytes
Bone resorption
Osteoclasts
Enchondral Dev’t Process
Hyaline Cartilage -> Invaded by blood vessels -> Replaced by bone
Membranous Dev’t Process
Osteoid matrix -> Calcifies -> Bone
Example of Enchondral bones
Sternum
Ribs
Scapulae
Spine
Pelvis
Long bones
Example of Membranous bones
Cranial Vault
Facial bones
BMD is influenced by:
Hormonal status
Dietary intake
Weight bearing activities
Peak of bone mass
1st 3 decades of life (35 y/o)
Pathophysiology of Osteoporosis
Reduced Osteoblastic activity
Increased Osteoclastic activity
MC area of fx in Osteoporosis
Midthoracic
Upper lumbar
Hip
Distal forearm
Modifiable Risk Factors (Osteoporosis)
Smoking
Alcoholism
Low Calcium intake
Early Pregnancy
Sedentary Lifestyle
Caffeine intake
Anorexia
Medication
Early Menarche
MC prescribed tx in Osteoporosis
Estrogen Therapy
MC form of short limb Dwarfism
Achondroplasia
Echondral Osteogenesis is retarded and ceased early
Achondroplasia
Characteristics of Achondroplasia
Brachycephalic
Small Face
Broad Forehead
Flat Nose
Prominent Jaw
Short Stature (4ft), Arms & Legs
Main en Trident
Bowing of Femur & Tibia
Milder form of Achondroplasia
Almost normal face & cranium
Hypochondroplasia
Normal Face & Cranium with short stature
Not obvious at birth (2 y/o)
Pseudoachondroplasia
Changes in Metaphysis that is similar to Rickets
Metaphyseal chondroplasia
Chondroectodermal Dysplasia AKA
Ellis-Van Creveld Syndrome
Chondroectodermal Dysplasia Manifestations
Polydactyly
Dysplastic Fingernails
Chondrodysplasia Punctata AKA
Stippled Epiphyses
Irregularly stippled calcification in epiphysis
Chondrodysplasia Punctata or Stippled Epiphyses
Facial Features seen in Chondrodysplasia Punctata
Mongoloid Facie