Fractures Flashcards
Primary therapies to make bone stronger
1
Q
Alendronate
A
Structural analogs of pyrophosphate = inhibit bone breakdown (osteoclasts: resorption) to increase bone density
2
Q
Denosunab
A
Monoclonal antibody targeting RANK in bone resorption pathway to decrease osteoclasts resorption & increase bone mass, strength
3
Q
Teriparatide
A
Like endogenous PTH (parathyroid) that stimulate new bone formation
4
Q
What is the drug class of Alendronate?
A
Bisphophonates
5
Q
What is an alternative drug to Alendronate?
A
Risedronate
6
Q
What drug class is Denosunab?
A
RANK = Receptor activator of nuclear factor kappa-B ligand inhibitor
7
Q
What is the drug class of Teriparatide?
A
Parathyroid hormone analogue
