Foundations 5 Flashcards
1
Q
In familial hypercholesterolemia the LDL receptor is mutated and unable to bind what intracellular protein?
A
Clatherin which in association with adaptin is responsible for endocytosis
2
Q
Which leukotriene receptor blocker is indicated in young asthmatics?
A
Montelukast
3
Q
What derivative of arachadonic acid is a neutrophil chemoattractant?
A
LTB4 (Neutrophils arrive B4 others)
4
Q
What effects to prostaglandins have on the uterus?
A
They function to increase uterine tone (induce labor)
5
Q
What cell membrane product is converted to arachadonic acid by phospholipase A2?
A
Phosphatidylinositol
