Fosphenytoin Flashcards

1
Q

Fosphenytoin

A

Pro-drug of phenytoin

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2
Q

Side effects - CV

A

Fosphenytoin IV = severe CV reactions:
- asystole
- ventricular fibrillation
- cardiac arrest
- hypotension
- bradycardia
- heart block

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3
Q

Monitoring

A
  • Monitor HR, BP and respiratory function for duration of infusion.
  • Observe patient for at least 30 minutes after infusion.
  • Hypotension = reduce infusion rate or discontinue.
  • Reduce dose/infusion rate in elderly, renal or hepatic impairment.
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