Formative quiz 1 Flashcards
What cell type is predominantly formed by the last wave of neural crest cells to leave the neural tube?
Melanocytes
What happens when you breathe in (inhalation)?
Breathing allows oxygen (which humans and a lot of other species need for survival) to enter the lungs, from where it can be absorbed into the bloodstream.
- The diaphragm contracts and moves down.
- The external intercostal muscles contract.
- The sternum moves forward.
- Neck muscles contract.
Charcot–Marie–Tooth disease is a congenital disorder that disrupts the myelin sheath of peripheral axons. Which cell type is most likely affected by this disorder?
Schwann cells
In the mammalian blastocyst, which one of the following tissues forms extra-embryonic mesoderm?
Epiblast
You have marked cells of the trunk neural crest soon after neural tube closure and then observed the distribution of these cells at the end of development. Which of the following cell-types would NOT be marked?
- Enteric neuron
- Sympathetic neuron
- Schwann cells
- Sensory neurons
- Melanocyte
Enteric neuron
Which of the following statements about Schwann cells is FALSE?
Select one:
- Schwann cells will only secrete the myelin sheath when in contact with the axons of motor-neurons.
- The myelin sheath secreted by Schwann cells helps saltatory conduction of the action potential.
- They differentiate in response to signals from axons.
- There are both myelinating and non-myelinating Schwann cells.
- Schwann cells are formed by trunk neural crest cells.
Schwann cells will only secrete the myelin sheath when in contact with the axons of motor-neurons.
Schwann cells are the principle glial cells of the peripheral nervous system. They wrap around axons and in many cases secrete the myelin sheath that helps saltatory conduction of the action potential.
The pancreas is a mixed exocrine and endocrine gland. What is its exocrine function?
The secretion of enzymes and salts involved in digestion
In the peripheral nervous system which of the following is not a division of the efferent system?
Viscerosensory
Which of the following statements is true of smooth muscle?
Select one:
- Has multiple nuclei in each cell.
- Involuntary
- Found in the diaphragm
- Fast contracting
- Clearly striated
Smooth muscle is an involuntary non-striated muscle found in organs such as the digestive system, reproductive system, respiratory system, skin, urinary system, and vasculature. It is slow to contract and slow to tire.
Hans Driesch (1893) dissociated 2-cell sea urchin embryos and allowed the blastomeres to develop separately. What happened to these blastomeres?
They formed half-sized but otherwise normal larvae.
A minority of separated blastomeres would have died but most formed half-sized but otherwise normal larvae. Since they have no external source of nutrition they cannot grow to normal size until they start to feed for themselves (unlike mammals).
Which of these statements applies to the phrenic nerves?
Select one:
Mixed autonomic nerves that supply the diaphragm
Sympathetic nerves that supply the diaphragm
Mixed autonomic and somatic nerves that supply the diaphragm
Somatic nerves that supply the diaphragm
Parasympathetic nerves that supply the diaphragm
Mixed autonomic and somatic nerves that supply the diaphragm
What defect might you observe following damage to cranial nerve III (oculomotor nerve)?
Defective movement of the eye.
The enteric nervous system is formed by neural crest cells from which region of embryonic neural tube?
The vagal region of the spinal cord.
Morphogens have been an important concept in developmental biology since the early 20th century. However, it wasn’t until 1988 that the first morphogen was described, the Drosophila protein Bicoid. What distinctive feature demonstrated that Bicoid was a morphogen?
It acts in a concentration dependent manner to specify different cell fates in the embryo.
Bicoid is a transcription factor that patterns the rostral half of the syncytial blastoderm stage Drosophila embryo. Because there are no cell membranes it can diffuse to form a gradient over the rostral half.
You have grafted the newly formed floor plate of a quail embryo into the dorsal half of a newly formed chick neural tube. What, if any, is the effect of this graft on the host neural tube.
The grafted floor plate induces ectopic motor-neurons in the host neural tube.