formative 5- endocrinology Flashcards
Which of the following is not under the control of the pituitary gland?
A. Thyroid
B. Adrenal cortex
C. Adrenal medulla
D. Testis
E. Ovary
C. Adrenal medulla
Which of the following statements is false?
A. The pituitary gland lies in
the sella turcica
B. The weight of the
pituitary gland is around
0.5g
C. ACTH is secreted from the
pituitary during stress
D. The pituitary regulates
calcium metabolism
E. The anterior and posterior
pituitary are distinct on an
MRI scan
D. The pituitary regulates
calcium metabolism
In men all the following are mainly produced in the adrenal cortex
except?
A. DHEAS
B. Testosterone
C. Aldosterone
D. 17-OH progesterone
E. Androstenedione
B. Testosterone
Which of the following regarding AVP is false?
A. AVP levels have a linear
relationship with serum
osmolality
B. is produced in the pituitary gland
C. stimulates reabsorption of
water in the collecting duct of the nephron
D. in hypotension baroreceptors predominantly activate ADH
production and secretion
E. Further AVP production is no longer effective once urine osmolality has reached a plateau
B. is produced in the pituitary gland
Where is growth hormone’s main site of action to stimulate IGF1 release?
A. Bone
B. Liver
C. Adrenal cortex
D. Muscle
E. Pancreas
B. Liver
The following are typical features of excess growth hormone secretion
except?
A. Polyuria
B. Joint pains
C. Sweating
D. Hypotension
E. Headaches
D. Hypotension
The following hormones all have a circadian rhythm except?
A. Cortisol
B. Testosterone
C. DHEA
D. 17OH progesterone
E. Thyroxine (T4)
E. Thyroxine (T4)
Typical features of cortisol deficiency include the following except?
A. Hypotension
B. Muscle aches
C. Weight loss
D. Hyperglycaemia
E. Lethargy
D. Hyperglycaemia
A 38 year old lady presented with weight gain,
menorrhagia and constipation. She is most likely to be suffering from?
A. Cushing’s syndrome
B. Addison’s disease
C. Primary
hypothyroidism
D. Graves disease
E. Acromegaly
C. Primary
hypothyroidism
Which test would you likely want to perform in a patient with proximal muscle weakness, purple striae and thin skin?
A. Synacthen test
B. Overnight
dexamethasone
suppression test
C. Insulin tolerance
test
D. Glucagon test
E. Skin allergy tests
B. Overnight
dexamethasone
suppression test
A 24 year old girl presented with hirsutism,
oligomenorrhoea and acne. What test would you likely carry out from the ones below?
A. Ultra sound adrenals
B. Ultra sound ovaries
C. MRI ovaries
D. CT scan adrenals
E. Prolactin
B. Ultra sound ovaries
A 54 year old gentleman presented with
hyponatraemia. All the following conditions need
excluding before confirming SIADH except?
A. Hypothyroidism
B. Hypervolaemia
C. Euvolaemia
D. Adrenal insufficiency
E. Diuretic use
C. Euvolaemia
A 66 year old gentleman had a serum sodium of 124 mmol/l, serum osmolality 265 mmol/l and a urine
sodium of 52 mmol/l. What would you like to perform
first?
A. Chest X-ray
B. CT brain
C. Skin turgor and jugular venous pressure test
D. Thyroid function tests
E. Synacthen test
C. Skin turgor and jugular venous pressure test
The following are most likely causes of SIADH except?
A. Multiple sclerosis
B. Lung abscess
C. Subdural haemorrhage
D. Lymphoma
E. Cerebrovascular accident
A. Multiple sclerosis
A 28 year old presented with a microprolactinoma?
What is the most unlikely symptom?
A. Galactorrhoea
B. Oligomenorrhoea
C. Decreased sexual appetite
D. Headaches
E. Visual field defects
E. Visual field defects