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Crime scene > Forensic Toxicology and Pharmacology > Flashcards

Forensic Toxicology and Pharmacology Flashcards

1
Q

Toxicology

A

The study of poisons

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2
Q

Postmortem Drug testing

A

Drug testing with the goal of determining whether drugs were the cause or contributing factor in a death

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3
Q

Work Place Drug Testing

A

Testing job applicants and employees for illegal drugs in their system

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4
Q

Absorption, Distribution, Metabolism, and Excretion (The stages in which a drug moves through the body)

A

ADME stands for

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5
Q

Opiates

A

A large class of drugs distinguished by their ability to caused euphoria and relieve pain. Includes: Oxycodone, Fentanyl, morphine, heroin

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6
Q

Depressants

A

Opiates are classified as…

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7
Q

Amphetamine

A

A large class of drugs that creates an excitatory condition, wakefulness and euphoria. Includes: methamphetamines,

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8
Q

Stimulants

A

Amphetamines are classified as…

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9
Q

Anorexic

A

Appetite Supressent

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10
Q

Cocaine

A

Substance derived from the erythroxylin cocoa plant that creates and excitatory condition, state of wakefulness and euphoria

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11
Q

Cannabinoids

A

Marijuana and other parts of the plant Cannabis with tetrahydrocannabinol (THC) as the active ingredient

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12
Q

Stimulant

A

Cocaine is classified as…

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13
Q

Depressants

A

Cannabinoids are classified as

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14
Q

Polypharmacy

A

A mixture of drugs

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15
Q
A
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16
Q
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17
Q
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18
Q
A
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19
Q

Opiates

A

Narcotics are classified as part of which group of

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20
Q

NIDA

A

National Institute of Drug Abuse

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21
Q

Arsenic

A

What poison is tasteless odorless and lethal in small doses?

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22
Q

Lead

A

What heavy metal causes a blue line along the gums?

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23
Q

Steroids?

A

Original treatment for hypogonadism?

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24
Q

Acetaldehyde

A

Alcohol produces____________ as it is metabolized in the liver

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25
Q

Designer Drug

A

Drug synthesized with particular pharmaceutical characteristics, designed for abuse and evasion of drug laws

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26
Q

Hallucinogen

A

Psychoactive drug that induces hallucinations or alters sensory experiences

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27
Q

Phencyclidine

A

A schedule I drug that causes uses to experience severe psychotic manifestations. Was once used as a surgical anesthetic

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28
Q

Vitreous Humor

A

Ocular fluid that is used as a sample for postmortem toxicology testing.

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29
Q

clandestine Drug Laboratoreis

A

Illicit location that manufactures controlled substances

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30
Q

Infrared Spectrophotometry ( IR Spectroscopy)

A

Using the absorption of infrared radiation to produce a chemical fingerprint of a substance.

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31
Q

Liquid/Liquid Extraction

A

Using a liquid to dissolve another liquid substance and remove it from a mixture

32
Q

Dry Extraction

A

Extraction uses a solvent to dissolve and remove the compound of interest

33
Q

Physical Extraction

A

Separating a compound by physical size

34
Q

Extraction

A

Separation of a compound of interest from the rest of the solution.

35
Q

Microcrystalline tests

A

A reaction between the compound of interest and chemical reagent that results in the formation of uniform crystals that can be observed with the microscope

36
Q

Wet Chemical Procedures

A

Procedures that involve solvents, extractions, ect. not instrumental

37
Q

Botanical Examinations

A

Study of various plant structures, such as roots, stems, branches, leaves, fruits, or flowers, that may be used to determine if the plants are controlled substances. (Marijuana, Peyote)

38
Q

ASTM

A

American Society for Testing and Materials

39
Q

SWGDRUG

A

Scientific Working Group for the Analysis of Seized Drugs

40
Q

Cutting Agents

A

Something added to a illicit drug to reduce its concetration

41
Q

Schedule V Drugs

A

Drugs with almost no risk for abuse/ addiction and many medical uses. ( Codeine cough medicines)

42
Q

Schedule IV drugs

A

Drugs with a fairly low risk for abuse and addiction with many accepted medical uses. ( Valium)

43
Q

schedule III Drugs

A

Drugs with a lower potential for abuse and addiction and accepted medical use. ( anabolic steroids, codeine and barbiturates)

44
Q

Schedule II Drugs

A

Drugs with a high potential for abuse and addiction but some accepted medical uses. ( Morphine, cocaine methamphetamine)

45
Q

Schedule I Drugs

A

Drugs with a high potential for abuse and addiction and no accepted medical application (Heroin, LSD, marijuana)

46
Q

Drug Enforcement Administration (DEA)

A

The US government agency responsible for regulation of controlled drugs

47
Q

Controlled Substances Act (CSA)

A

Legislation in the US that defines illegal drugs and classifies them by Schedules

48
Q

Postmortem Redistribution

A

Concentration changes in a drug that occur after death as the drug is redistributed throughout the body.

49
Q

LD50

A

Dose of poison that kill 50% of the population

50
Q

Toxicokinetics

A

How drugs and poisons move through the body

51
Q

Toxicogenomics

A

A device used to characterize color using a spectrometer. Used to test for the presence of metals.

52
Q

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

A

A form of mass spectrometry used to detect inorganic materials and metals

53
Q

Colorimetric testing

A

A persons genetic factors that effect the efficacy of a drug or poison in their system

54
Q

Tandem Mass Spectrometers (LC-MS^n)

A

the leading technique in sequence determination of peptides and other biomolecule

55
Q

LC-MS

A

Analytical instrument that combines a liquid chromatography with a mass spectrometery. Detects more compounds than than GC-MS

56
Q

Carbon Monoxide

A

Toxic gas that is formed in combustion. This gas binds to hemoglobin more tightly than blood and prevents the blood from carrying oxygen. Levels above 60% in the blood are fatal.

57
Q

Methemoglobin

A

Oxidized form of hemoglobin. The antidote to cyanide poisoning.

58
Q

Immunoassays

A

Tests using antibodies that react with a drug or substance that recognizes the antibody

59
Q

Thin-Layer Chromatography (TLC)

A

The use of a solvent that travels through a porous medium to separate compounds based on their chemical affinity with the solvent and the medium

60
Q

GC-MS

A

Acronym of Gas Chromatography with Mass Spectrometry

61
Q

Depressants

A

Cannabinoids are classified as..

62
Q

Polypharmacy

A

A mixture of drugs

63
Q

Stimulant

A

Cocaine is classified as…

64
Q

Gas Chromatography

A

Gas flowing through a coated tube separates compounds by their size, weight and chemical reactivity with the coating of the tube or column

65
Q

Cyanide

A

Toxic chemical inhibits the electron transport chain in the mitochondria of cells. Most toxic in its gaseous state. Levels above 2500 ng/ml are fatal.

66
Q

Cannabinoids

A

Marijuana and other parts of the plant Cannabis with tetrahydrocannabinol (THC) as the active ingredient

67
Q

Depressants

A

Opiates are classified as…

68
Q

Amphetamine

A

A large class of drugs that creates an excitatory condition, wakefulness and euphoria. Includes: methamphetamines,

69
Q

Stimulants

A

Amphetamines are classified as…

70
Q

Anorexic

A

Appetite Supressent

71
Q

Cocaine

A

Substance derived from the erythroxylin cocoa plant that creates and excitatory condition, state of wakefulness and euphoria

72
Q

Opiates

A

A large class of drugs distinguished by their ability to caused euphoria and relieve pain. Includes: Oxycodone, Fentanyl, morphine, heroin

73
Q

Absorption, Distribution, Metabolism, and Excretion (The stages in which a drug moves through the body)

A

ADME stands for

74
Q

Work Place Drug Testing

A

Testing job applicants and employees for illegal drugs in their system

75
Q

Postmortem Drug testing

A

Drug testing with the goal of determining whether drugs were the cause or contributing factor in a death

76
Q

Toxicology

A

The study of poisons

Crime scene (5 decks)

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