Forensic Toxicolgy and pharmacology pt2 Flashcards
Toxicology
a branch of biology, chemistry, and medicine (more specifically pharmacology) concerned with the study of the adverse effects of chemicals on living organisms.
postmortem drug testing
The branch of toxicology focused on the analysis of biofluids after death of the body.
workplace drug testing
A branch of toxicology focused on analysis of employee samples
biofluids
Blood, urine, bile, etc.; fluids obtained from the body
ADME
The process by which a drug moves through the body: absorption, distribution, metabolism and excretion
Opiates
A term for the class of narcotic drugs derived from the opium plant, including morphine and codeine. heroin is produced from morphine
depressants
Substance that depress the central nervous system and cause symptoms such as slowed heart rate and breathing
amphetamine
A controlled substance that, along with its analogs such as methamphetamine, creates an excitatory condition (stimulation), state of weakfulness, and euphoria
stimulants
Drugs that produce produces a temporary increase of functional activity or efficiency
precursors
Substances that can be converted into an abused substances
cocaine
A control substance derived from the erythroxylin cocoa plant that creates an excitatory condition (stimulation), state of wakefulness, and euphoria
cannabiboids
A term applied to marijuana and parts of the plant Cannabis sativa in which tetrahydrocannabinol (THC) is the active
Tetrahydricannabinol (THC)
The active ingredient in Marijuana
Polypharmacy
A mixture of drugs
volume of distribution
An equation that relates dose of a drug to blood concentration
Gas chromatography
Gas flowing through a coated tube separates compounds by their size, weight, and chemical reactivity with the coating of the cube or column
Cyanide
A highly toxic chemical, especially in the form of gas (hydorgen cyanide)
methemoglobin
An oxidized form of hemoglobin.
cyanomethemoglobin
A complex of cyanide and methemoglobin; used to treat cyanide posioning
carboxyhemoglobin
Hemoglobin in which the oxygen has been replaced by carbon monoxide (CO)
thin layer chromatography (TLC)
The use of a solvent that travels through a porous medium to separate compounds based on their chemical affinity with the solvent and the medium
mobile phase
In a chromatographic system such as thin layer chromatography or gas chromatography, the phase that moves.