Forensic Toxicology And Pharamacology Flashcards
Toxicology
Study of poisons.
Postmortem drug tests
Drug testing the goal of determining whether drugs were the cause or contributing factor in a death.
Workplace drug testing
Testing job applicants and employees for illegal drugs in there system.
ADME stands for-
Absorption, distribution, metabolism, and excretion. (The stages in which a drug moves through the body)
Opiates
A large class of of drug is distinguished by their ability to cause euphoria and relieve pain. Includes: oxycodone, fetanyl, morphine, and heroin.
Opiates are classified as:
Depressants
Amphetamine
A large of drugs that creates an excitatory condition, wakefulness and euphoria. Includes: methamphetamines.
Amphetamines are classified as:
Stimulants
Anorexic.
Appetite suppressants.
Cocaine
A substance deprived from erythromycin cocoa plant that creates an excitatory condition state of wakefulness and euphoria. S
Cannabinoids
Marijuana and other parts of the plant cannabis with tetrahydrocannabinol (THC) as the active ingredient.
Cocaine is classified as
Stimulant
Cannabinoids are classified as
Depressants
Polypharmacy
A mixture of drugs
Gas chromatography
Gas flowing through a coated tube separates compounds by their size, weight, and chemical reactivity with the coating of the tube or column.
Cyanide
Toxic chemical inhibits the electron transport chain in the mitochondria of cells. Most fatal toxic in its gaseous state is levels above 2509 ng/ml are fatal.
Carbon monoxide
The toxic gas that if formed in combustion. This gas binds to hemoglobin tightly than blood and prevents the blood from carrying oxygen. Levels above 60% in the blood are fatal.
Methemoglobin
Oxidized form of hemoglobin. The antidote to cyanide poisoning.
Immunoassays
Tests using antibodies that react with a drug or substance that recognizes the antibody.
Thin layer chromatography (TLC)
The use of a solvent that travels thought a porpoise medium to separate compounds based on their chemical affinity with the solvent and the medium.
GC-MS
Acronym of gas chromatography with mass spectrometry
Mass spectroscopy
Technique based on the detection of vaporized molecules and their ironized fragments. The detection and display of the spectra are based on the mass-to-charge ratios of the ions.
LC-MS
An analytical instruments that combines a liquid chromatography with a mass spectrometry. Detects more compounds than GC-MS.
Tandem mass of spectrometry (LC-MS^n)
A detection system with more than one masss spectrometer in a series. (refers to the number of MS units)
