FOREBRAIN : basal ganglia Flashcards
1
Q
Basal ganglia
\+ 3 nuclei \+ 2 diseases
A
- > planning goal directed actions
- > ensuring smooth movement / coordination
nuclei
- Globus pallidus
- Putamen
- Caudate nucleus
diseases
- Parkinson’s
- Huntington’s
2
Q
Globus pallidus
A
- > movement inhibition
- > internal -> infromation relay
- > external -> sends info. to thalamus
3
Q
Putamen
A
mediating movement + coordination
4
Q
Caudate nucleus
A
+ putamen = STRATIUM
5
Q
Parkinson’s disease
A
breakdown of dopaminergic neurons
-> SUBSTANTIA NIGRA
subthalamic nucleus overactivation
-> ‘‘pausing’’ GLOBUS PALLIDUS -> shutdown of motion
symptoms
- > tremors / slowed movement
- > impaired posture + balance
- > loss of automatic movement
- > speech + writing changes
6
Q
Huntington’s disease
A
degeneration of basal ganglia
-> CAUDATE NUCLEUS + PUTAMEN
symptoms
- > rapid involuntary movement
- > brief muscle contraction -> jerking
- > uncoordinated + slow movement
- > irritability / excitability / agitation