Forebrain and Limbic System Flashcards
What makes up the diencephalon?
the epithalamus, subthalamus, thalamus and hypothalamus
What makes up the epithalamus?
the pineal gland and habenula
What does the pineal gland do?
secrete melatonin during darkness to regulate sleep and wake cycles
what are the inputs and outputs to the habenula?
major input is from the stria medullaris (limbic system reward behavior) and major output is the habenulointerpeduncular tract which is important for REM sleep cycles
What are the subdivisions of the thalamic nuclei?
anterior division (AN), medial division (DM) and lateral division which includes the dorsal tier (LD and LP) and ventral tier (VA/VL, VPL, MGN and LGN), intralaminar, reticular and midline nuclei
What separates the subdivisions of the internal medullary lamina
the internal medullary lamina (IML)
what are the 2 thalamic inputs?
either specific inputs (direct) or regulatory inputs that receive the specific input information, manipulate it and then send it out (indirect)
what are the three types of thalamic nuclei?
relay, association and intralaminar/midline nuceli
What are relay nuclei?
thalamic nuclei that receive information from a “tract” and send it to a specific spot on the cortex
ex. (ML to VPL to specific spot on cortex to VPL)
what are association nuclei?
thalamic nuclei that come from a specific spot on the association cortex
what are intralaminar/midline nuclei?
receive distinct information from things that are not a tract or the cortex
ex. (basal ganglia or limbic structures)
- project to cortex, basal ganglia and limbic structures
Thalamic nuclei all consist of either…
projection neurons or interneurons (inhibitory)
what are reticular nuclei?
important source of regulatory input to the thalamus. No projections to the cortex, the cortex and thalamus send collaterals to the reticular nuclei. They are inhibitory axons to the thalamus
what is the function of the medial geniculate nucleus?
relay nucleus for hearing (auditory cortex projections)
what is the function of the lateral geniculate nucleus?
relay nucleus for vision (primary visual cortex in the occipital lobe)
what is the function of the ventral posterior medial nucleus?
sensory relay nucleus for the face (trigeminal nerve information)
what is the function of the ventral posterior lateral nucleus?
sensory relay nucleus for the body
what is the function of the ventral anterior/lateral nucleus?
motor relay nucelus
what is the function of the anterior nucleus?
relay nucleus for the limbic system (hippocampal information)
what is the function of the intralaminar nucleus?
component of the reticular activating system
Most of the thalamus is made up of?
association nuclei
what are the two main association nuclei of the thalamus, where do they project and what is the areas function?
- the dorsomedial (DM) projects to the prefrontal cerebrum which controls foresight
- The Pulvinar-LP complex which projects to the very large parietal-occipital temporal region which activity is unknown but may be for visual perception and attention
what does the internal capsule do?
its a passageway for all the fibers from the thalamus to reach the cortex and the cortex to reach the thalamus
-forms the cerebral peduncle which the corticospinal, bulbar and pontine fibers descend
what are the 5 parts of the internal capsule and their relationship to the lenticular nucleus?
anterior limb: between caudate and lent nuc
posterior limb: btwn thalamus and lent nuc
genu: btwn ant. and post. limb
retrolenticular: behind the lent nuc
sublenticular: beneath the lent nuc
clinically, what limb of the internal capsule is the most important?
posterior, strokes