Fondaparinux Flashcards

1
Q

Fondaparinux: administration

A

. injectable: sous-cutanée (seulement)

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2
Q

Fondaparinux: activité

A

. anti-Xa

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3
Q

Fondaparinux: demie-vie

A

. 17-21h

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4
Q

Fondaparinux: élimination

A

. rénale

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5
Q

Fondaparinux: biodisponibilité

A

. 100%

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6
Q

Fondaparinux: T prophylactique en médecine

A

. 2,5 mg/ 0,5 mL SC/ j

. pendant 7 - 14 jours

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7
Q

Fondaparinux: T prophylactique, si chirurgie à risque modéré

A

. 2,5 mg/ 0,5 mL SC/ J

. 2 heures après l’intervention

. pendant 5-9 jours après Prothèse de Genoux

. pendant 35 jours après Prothèse de Hanche

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8
Q

Fondaparinux: T curatif

A

. 7,5 mg SC/ j

. si patient < 50 kg: 5 mg/j

. si patient > 100 kg: 10 mg/j

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9
Q

Fondaparinux: survaillence de l’activité

A

. aucune

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10
Q

Fondaparinux: surveillance des plaquettes

A

. aucune

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11
Q

Fondaparinux: contre-indications

A

. hypersensibilité
. saignement évolutif
. endocardite aigue bactérienne
. anesthésie péridurale ou rachianesthésie
. IR sévère (DFG < 30 mL/min), prudence si DFG < 50 mL/min
. femme enceinte ou allaitement

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12
Q

Fondaparinux: antidote

A

. non

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