Fluoroquinolones Flashcards
1
Q
Mechanism of action, fluorquinolones ?
A
Broad spectrum, works by the inhibition of Topoisomerase 2 &4 (DNA gyrase), necessary for DNA transcription, repair, strand supercoiling repair &recombination.
2
Q
Fluoroquinolones, indications ?
A
urinary tract infections,acute cystitis,prostatitis,
lower respiratory sys. infections, acute sinusitis,
skin &skin structure infections,
bone &joint infections,
infectious diarrhea,
gonorrhea, anthrax.
3
Q
Ciprofloxacine, generics available ?
A
Ciprolfloxacine 500mg
Ciprolon 250mg
Flocine 250mg
