Fluoroquinolone Antibiotics Flashcards
1
Q
How do fluroquinolones work?
A
They inhibit nucleic acid synthesis
2
Q
Name the common fluroquinoles.
A
- Ciprofloxacin
- Levofloxacin
- Moxifloxacin
3
Q
Which infections are fluroquinolones indicated for?
A
Broad spectrum including pseudomonas, for;
- Urinary tract infection
- Prostatitis
- Atypical and hospital-acquired chest infection
- Infectious diarrhoea
4
Q
What are the side effects of fluroquinolones?
A
- GI irritation
- CNS effects (decreased seizure threshold, headache, drowsiness, mood change)
- Peripheral neuropathy
- Tendinopathy (achilles)
- Increase in QT interval
- Clostridium difficile infection
