Fluoride & desensitizing agents Flashcards
what is fluoride
- naturally occurring mineral
what happens with consumption of excess fluoride during tooth formation
- enamel hypoplasia
what is the acceptable quantity of fluoride in water
- 0.7-1.2 ppm
what is the mechanism of action for fluoride (3)
- inhibits demineralization
- enhances remineralization
- inhibits bacteria in the biofilm
how does fluoride inhibit demineralization
- fluoride in fluid of biofilm around enamel crystals and dentin of root
- passes through the diffusion channels with the acids
- increases the fluoride of the subsurface lesion
- prevents the continued dissolution of the minerals in enamel and dentin
how does fluoride enhance remineralization
- fluoride absorbs to mineral crystals within the tooth and attracts calcium ions
- fluoride ions incorporate into the remineralizing tooth structure, resulting in the development of fluorapatite-like crystals
- fluoride levels in the mouth from fluoridated water are sufficient to enhance remineralization
does topical or systemic have a better benefit for fluoride
- greatest anti-caries benefit from topical exposure after eruption
- fluoride in saliva – incorporated into enamel crystals during remineralization
- evidence of fluoride remaining in saliva several hours – prolonger topical effect
what is the pH for tooth minerals and fluorapatite crystals
- tooth minerals dissolve at pH of 5.5
- fluorapatite dissolves at pH of 4.5
what causes erosion
- highly acidic foods and beverages
- medical conditions
how does erosion differ from caries
- not bacteria causing erosion - environment
2. minerals of the tooth that are lost
how does fluoride cause bacterial inhibition
- fluoride interferes with essential enzyme activity of bacteria
- crosses the bacterial wall (membrane) as hydrofluoric acid
- alkaline cytoplasm - fluoride ion, causes enzyme activity disruption of bacteria = death
what is substantivity
- the prolonged effect achieved when a chemical is released slowly over time
what are active ingredients in antibacterial rinses
- essential oils
- cetylpyridinium chloride
- triclosan
- ACS = acidified sodium chlorite
- PHMB = polyhaxamethylene biguanine
what does chlorhexidine do
- bactericidal
- opens the cell membrane
- recommended to be used in high risk individuals only, 1 min daily for 1 week/month and must be used in conjunction with fluoride remineralization therapy
- chx binds strongly onto many sites: mucous membranes and biofilm
- the bactericidal effect from a single dose is greatest for several hours, could even last as long as 5 days
what is chlorhexidine gluconate
- percentage concentration: ~2% in Europe, ~12% in usa and canada
- common names: peridex, periogard, oris chx
what is chlorhexidine gluconate the most effective agent for the reduction of
- biofilm = 55%
- gingivitis: 45%
what are side effects of chx
- brown stain on: teeth and tongue; composites, glass ionomer and compomers; acrylic teeth (dentures)
- bitter taste
- diet and brushing habits
- more frequent professional cleanings
what are phenolic compounds in essential oil rinses and what are the percentages of the phenolic compounds
- thymol = 0.063% - Listerine, 0.064% - Personelle
- eucalyptol = 0.091% - Listerine, 0.092% - Personelle
- menthol = 0.042% - Listerine, 0.042% - Personelle
what are 3 commercial rinses with phenolic compounds
- listerine
2. personelle and life
what are the 3 methods of delivery of topical fluoride
- drinking water and some beverages
- self applied: non prescription OTC products, prescription products
- professionally applied: prescription products
what is the fluoride content in over the counter self applied dentifrices
- 1000 ppm fluoride:
- sodium fluoride: crest pro health and Colgate total
- sodium monofluorophosphate (NaMFP)
- stannous fluoride (SnF2)
- 5000 ppm fluoride:
- prevident 1.1% NaF
what is the fluoride content in percentage in a weekly vs daily mouthrinse
- weekly: 0.2% NaF
- daily: 0.05% = 230 ppm of NaF, 0.4% SnF2