Fluids and Electrolytes Chapter18 P107-123 Flashcards
What are the two major body fluid compartments?
P107
- Intracellular
2. Extracellular
What are the two subcompartments of extracellular fluid?
P107
- Interstitial fluid (in between cells)
2. Intravascular fluid (plasma)
What percentage of body weight is in fluid?
P107 (picture)
60%
What percentage of body fluid is intracellular?
P108
66%
What percentage of body fluid is extracellular?
P108
33%
What is the composition of body fluid?
P108
Fluids = 60% total body weight:
Intracellular = 40% total body weight
Extracellular = 20% total body weight
(Think: 60, 40, 20)
How can body fluid distribution by weight be remembered?
P108
“TIE”:
T = Total body fluid = 60% of body weight
I = Intracellular = 40% of body weight
E = Extracellular = 20% of body weight
On average, what percentage of body weight does blood
account for in adults?
P108
≈7%
How many liters of blood
are in a 70-kg man?
P108
0.07 x 70 = 5 liters
What are the fluid requirements every 24 hours for each of the following substances:
1. Water
P108
≈30 to 35 mL/kg
What are the fluid requirements every 24 hours for each of the following substances:
2. Potassium
P108
≈1 mEq/kg
What are the fluid requirements every 24 hours for each of the following substances:
3. Chloride
P108
≈1.5 mEq/kg
What are the fluid requirements every 24 hours for each of the following substances:
4. Sodium
P108
≈1–2 mEq/kg
What are the levels and sources of normal daily water loss?
P108
Urine—1200 to 1500 mL (25–30 mL/kg)
Sweat—200 to 400 mL
Respiratory losses—500 to 700 mL
Feces—100 to 200 mL
What are the levels and sources of normal daily electrolyte loss?
P108
Sodium and potassium = 100 mEq
Chloride = 150 mEq
What are the levels of sodium and chloride in sweat?
P109
≈40 mEq/L
What is the major electrolyte in colonic feculent fluid?
P109
Potassium—65 mEq/L
What is the physiologic response to hypovolemia?
P109
Sodium/H2O retention via renin → aldosterone, water retention via ADH, vasoconstriction via angiotensin II and
sympathetics, low urine output and tachycardia (early), hypotension (late)
THIRD SPACING
What is it?
P109
Fluid accumulation in the interstitium of tissues, as in edema, e.g., loss of fluid into the interstitium and lumen of a paralytic bowel following surgery (think of the intravascular and intracellular spaces as the first two spaces)
THIRD SPACING
When does “third-spacing” occur postoperatively?
P109
Third-spaced fluid tends to mobilize back into the intravascular space around POD #3 (Note: Beware of fluid overload once the fluid begins to return to the intravascular
space); switch to hypotonic fluid and decrease IV rate
THIRD SPACING
What are the classic signs of third spacing?
P109
Tachycardia
Decreased urine output
THIRD SPACING
What is the treatment?
P109
IV hydration with isotonic fluids
THIRD SPACING
What are the surgical causes of the following conditions:
Metabolic acidosis
P109
- Loss of bicarbonate: diarrhea, ileus, fistula, high-output ileostomy, carbonic anhydrase inhibitors
- Increase in acids: lactic acidosis (ischemia), ketoacidosis, renal failure, necrotic tissue
THIRD SPACING
What are the surgical causes of the following conditions:
Hypochloremic alkalosis
P109
NGT suction, loss of gastric HCl through vomiting/NGT
THIRD SPACING
What are the surgical causes of the following conditions:
Metabolic alkalosis
P110
Vomiting, NG suction, diuretics, alkali ingestion, mineralocorticoid excess
THIRD SPACING
What are the surgical causes of the following conditions:
Respiratory acidosis
P110
Hypoventilation (e.g., CNS depression), drugs (e.g., morphine), PTX, pleural effusion, parenchymal lung disease,
acute airway obstruction
THIRD SPACING
What are the surgical causes of the following conditions:
Respiratory alkalosis
P110
Hyperventilation (e.g., anxiety, pain, fever, wrong ventilator settings)
THIRD SPACING
What is the “classic” acidbase finding with significant
vomiting or NGT suctioning?
P110
Hypokalemic hypochloremic metabolic alkalosis
THIRD SPACING
Why hypokalemia with NGT suctioning?
P110
Loss in gastric fluid—loss of HCl causes
alkalosis, driving K⁺ into cells
THIRD SPACING
What is the treatment for hypokalemic hypochloremic
metabolic alkalosis?
P110
IVF, Cl⁻/K⁺ replacement
THIRD SPACING
What is paradoxic alkalotic aciduria?
P110
Seen in severe hypokalemic, hypovolemic, hypochloremic metabolic alkalosis with paradoxic metabolic alkalosis of serum and acidic urine
THIRD SPACING
How does paradoxic alkalotic aciduria occur?
P110
H⁺ is lost in the urine in exchange for Na⁺ in an attempt to restore volume
THIRD SPACING
With paradoxic alkalotic aciduria, why is H⁺ preferentially lost?
P110
H⁺ is exchanged preferentially into the
urine instead of K⁺ because of the low
concentration of K⁺
THIRD SPACING
What can be followed to assess fluid status?
P110
Urine output, base deficit, lactic acid, vital signs, weight changes, skin turgor, jugular venous distention (JVD), mucosal membranes, rales (crackles), central venous
pressure, PCWP, chest x-ray findings
THIRD SPACING
With hypovolemia, what changes occur in vital signs?
P110
Tachycardia, tachypnea, initial rise in diastolic blood pressure because of clamping down (peripheral vasoconstriction) with subsequent decrease in both
systolic and diastolic blood pressures
THIRD SPACING
What are the insensible fluid losses?
P111
Loss of fluid not measured:
a) Feces—100 to 200 mL/24 hours
b) Breathing—500 to 700 mL/24 hours
(Note: increases with fever and tachypnea)
c) Skin—≈300 mL/24 hours, increased with fever; thus, insensible fluid loss is not directly measured
THIRD SPACING
What are the quantities of daily secretions:
Bile
P111
≈1000 mL/24 hours
THIRD SPACING
What are the quantities of daily secretions:
Gastric
P111
≈2000 mL/ 24 hours
THIRD SPACING
What are the quantities of daily secretions:
Pancreatic
P111
≈600 mL/ 24 hours
THIRD SPACING
What are the quantities of daily secretions:
Small intestine
P111
≈3000 mL/day
THIRD SPACING
What are the quantities of daily secretions:
Saliva
P111
≈1500 mL/24 hours
Note: almost all secretions are reabsorbed
THIRD SPACING
How can the estimated levels of daily secretions from bile,
gastric, and small-bowel sources be remembered?
P111
Alphabetically and numerically: BGS and 123 or B1, G2, S3, because Bile, Gastric, and Small bowel produce roughly 1 L,
2 L, and 3 L, respectively!
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What comprises normal saline (NS)?
P111
154 mEq of Cl⁻
154 mEq of Na⁺
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What comprises 1/2 NS?
P111
77 mEq of Cl⁻
77 mEq of Na⁺
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What comprises 1/4 NS?
P111
39 mEq of Cl⁻
39 mEq of Na⁺
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What comprises lactated Ringer’s (LR)?
P111
130 mEq Na⁺ 109 mEq Cl⁻ 28 mEq lactate 4 mEq K⁺ 3 mEq Ca⁺
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What comprises D5W?
P111
5% dextrose (50 g) in H(2)O
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What accounts for tonicity?
P112
Mainly electrolytes; thus, NS and LR are both isotonic, whereas 1/2 NS is hypotonic to serum
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
What happens to the lactate in LR in the body?
P112
Converted into bicarbonate; thus, LR cannot be used as a maintenance fluid because patients would become alkalotic
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
IVF replacement by anatomic site:
Gastric (NGT)
P112
D5 1/2 NS + 20 KCl
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
IVF replacement by anatomic site:
Biliary
P112
LR+/-sodium bicarbonate
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
IVF replacement by anatomic site:
Pancreatic
P112
LR+/-sodium bicarbonate
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
IVF replacement by anatomic site:
Small bowel (ileostomy)
P112
LR
COMMON IV REPLACEMENT FLUIDS (ALL VALUES ARE PER LITER)
IVF replacement by anatomic site:
Colonic (diarrhea)
P112
LR+/-sodium bicarbonate
CALCULATION OF MAINTENANCE FLUIDS
What is the 100/50/20 rule?
P112
Maintenance IV fluids for a 24-hour period:
100 mL/kg for the first 10 kg
50 mL/kg for the next 10 kg
20 mL/kg for every kg over 20 (divide by 24 for hourly rate)
CALCULATION OF MAINTENANCE FLUIDS
What is the 4/2/1 rule?
P112
Maintenance IV fluids for hourly rate:
4 mL/kg for the first 10 kg
2 mL/kg for the next 10 kg
1 mL/kg for every kg over 20
CALCULATION OF MAINTENANCE FLUIDS
What is the maintenance for a 70-kg man?
P112
Using 100/50/20: 100 x 10 kg = 1000 50 x 10 kg = 500 20 x 50 kg = 1000 Total = 2500 Divided by 24 hours = 104 mL/hr maintenance rate
Using 4/2/1: 4 x 10 kg = 40 2 x 10 kg = 20 1 x 50 kg = 50 Total = 110 mL/hr maintenance rate
CALCULATION OF MAINTENANCE FLUIDS
What is the common adult maintenance fluid?
P113
D5 1/2 NS with 20 mEq KCl/L
CALCULATION OF MAINTENANCE FLUIDS
What is the common pediatric maintenance fluid?
P113
D5 1/4 NS with 20 mEq KCl/L (use 1/4 NS because of the decreased ability of children to concentrate urine)
CALCULATION OF MAINTENANCE FLUIDS
Why should sugar (dextrose) be added to maintenance
fluid?
P113
To inhibit muscle breakdown
CALCULATION OF MAINTENANCE FLUIDS
What is the best way to assess fluid status?
P113
Urine output (unless the patient has cardiac or renal dysfunction, in which case central venous pressure or wedge pressure is often used)
CALCULATION OF MAINTENANCE FLUIDS
What is the minimal urine output for an adult on
maintenance IV?
P113
30 mL/hr (0.5 cc/kg/hr)
CALCULATION OF MAINTENANCE FLUIDS
What is the minimal urine output for an adult trauma
patient?
P113
50 mL/hr
CALCULATION OF MAINTENANCE FLUIDS
How many mL are in 12 oz (beer can)?
P113
356 mL
CALCULATION OF MAINTENANCE FLUIDS
How many mL are in 1 oz?
P113
30 mL
CALCULATION OF MAINTENANCE FLUIDS
How many mL are in 1 tsp?
P113
5 mL
CALCULATION OF MAINTENANCE FLUIDS
What are common isotonic fluids?
P113
NS, LR
CALCULATION OF MAINTENANCE FLUIDS
What is a bolus?
P113
Volume of fluid given IV rapidly (e.g., 1 L over 1 hour); used for increasing intravascular volume, and isotonic fluids should be used (i.e., NS or LR)
CALCULATION OF MAINTENANCE FLUIDS
Why not combine bolus fluids with dextrose?
P113
Hyperglycemia may result
CALCULATION OF MAINTENANCE FLUIDS
What is the possible consequence of hyperglycemia in
the patient with hypovolemia?
P114
Osmotic diuresis
CALCULATION OF MAINTENANCE FLUIDS
Why not combine bolus fluids with a significant amount of
potassium?
P114
Hyperkalemia may result (the potassium in LR is very low: 4 mEq/L)
CALCULATION OF MAINTENANCE FLUIDS
Why should isotonic fluids be given for resuscitation
(i.e., to restore intravascular volume)?
P114
If hypotonic fluid is given, the tonicity of the intravascular space will be decreased and H(2)O will freely diffuse into the
interstitial and intracellular spaces; thus, use isotonic fluids to expand the intravascular space
CALCULATION OF MAINTENANCE FLUIDS
What portion of 1 L NS will stay in the intravascular
space after a laparotomy?
P114
In 5 hours, only ≈200 cc (or 20%) will remain in the intravascular space!
CALCULATION OF MAINTENANCE FLUIDS
What is the most common trauma resuscitation fluid?
P114
LR
CALCULATION OF MAINTENANCE FLUIDS
What is the most common postoperative IV fluid after
a laparotomy?
P114
LR or D5LR for 24 to 36 hours, followed by maintenance fluid
CALCULATION OF MAINTENANCE FLUIDS
After a laparotomy, when should a patient’s fluid be
“mobilized”?
P114
Classically, POD #3; the patient begins to “mobilize” the third-space fluid back into the intravascular space
CALCULATION OF MAINTENANCE FLUIDS
What IVF is used to replace duodenal or pancreatic fluid
loss?
P114
LR (bicarbonate loss)
ELECTROLYTE IMBALANCES
What is a common cause of electrolyte abnormalities?
P114
Lab error!
ELECTROLYTE IMBALANCES
What is a major extracellular cation?
P114
Na⁺
ELECTROLYTE IMBALANCES
What is a major intracellular cation?
P114
K⁺
HYPERKALEMIA
What is the normal range for potassium level?
P115
3.5–5.0 mEq/L
HYPERKALEMIA
What are the surgical causes of hyperkalemia?
P115
Iatrogenic overdose, blood transfusion, renal failure, diuretics, acidosis, tissue destruction (injury/hemolysis)
HYPERKALEMIA
What are the signs/ symptoms?
P115
Decreased deep tendon reflex (DTR) or areflexia, weakness, paraesthesia, paralysis, respiratory failure
HYPERKALEMIA
What are the ECG findings?
P115
Peaked T waves, depressed ST segment, prolonged PR, wide QRS, bradycardia, ventricular fibrillation
HYPERKALEMIA
What are the critical values?
P115
K⁺ >6.5
HYPERKALEMIA
What is the urgent treatment?
P115
- IV calcium (cardioprotective), ECG monitoring
- Sodium bicarbonate IV (alkalosis drives K⁺ intracellularly)
- Glucose and insulin
- Albuterol
- Sodium polystyrene sulfonate (Kayexalate) and furosemide (Lasix)
- Dialysis
HYPERKALEMIA
What is the nonacute treatment?
P115
Furosemide (Lasix), sodium polystyrene sulfonate (Kayexalate)
HYPERKALEMIA
What is the acronym for the treatment of acute symptomatic hyperkalemia?
P115
“CB DIAL K”:
Calcium
Bicarbonate
Dialysis Insulin/dextrose Albuterol Lasix Kayexalate
HYPERKALEMIA
What is “pseudohyperkalemia”?
P115
Spurious hyperkalemia as a result of
falsely elevated K⁺ in sample from
sample hemolysis
HYPERKALEMIA
What acid-base change lowers the serum potassium?
P116
Alkalosis (thus, give bicarbonate for hyperkalemia)
HYPERKALEMIA
What nebulizer treatment can help lower K⁺ level?
P116
Albuterol
HYPOKALEMIA
What are the surgical causes?
P116
Diuretics, certain antibiotics, steroids, alkalosis, diarrhea, intestinal fistulae, NG aspiration, vomiting, insulin, insufficient supplementation, amphotericin
HYPOKALEMIA
What are the signs/symptoms?
P116
Weakness, tetany, nausea, vomiting, ileus, paraesthesia
HYPOKALEMIA
What are the ECG findings?
P116
Flattening of T waves, U waves, ST segment depression, PAC, PVC, atrial fibrillation
HYPOKALEMIA
What is a U wave?
P116 (picture)
(see picture)
HYPOKALEMIA
What is the rapid treatment?
P116
KCl IV
HYPOKALEMIA
What is the maximum amount that can be given through a peripheral IV?
P116
10 mEq/hour
HYPOKALEMIA
What is the maximum amount that can be given through a central line?
P116
20 mEq/hour
HYPOKALEMIA
What is the chronic treatment?
P116
KCl PO
HYPOKALEMIA
What is the most common electrolyte-mediated ileus in
the surgical patient?
P116
Hypokalemia
HYPOKALEMIA
What electrolyte condition exacerbates digitalis toxicity?
P117
Hypokalemia
HYPOKALEMIA
What electrolyte deficiency can actually cause hypokalemia?
P117
Low magnesium
HYPOKALEMIA
What electrolyte must you replace first before replacing K⁺?
P117
Magnesium
HYPOKALEMIA
Why does hypomagnesemia make replacement of K⁺ with hypokalemia nearly impossible?
P117
Hypomagnesemia inhibits K⁺ reabsorption from the renal tubules
HYPERNATREMIA
What is the normal range for sodium level?
P117
135–145 mEq/L
HYPERNATREMIA
What are the surgical causes?
P117
Inadequate hydration, diabetes insipidus, diuresis, vomiting, diarrhea, diaphoresis, tachypnea, iatrogenic (e.g., TPN)
HYPERNATREMIA
What are the signs/ symptoms?
P117
Seizures, confusion, stupor, pulmonary or peripheral edema, tremors, respiratory paralysis
HYPERNATREMIA
What is the usual treatment supplementation slowly over
days?
P117
D5W, 1/4 NS, or 1/2 NS
HYPERNATREMIA
How fast should you lower the sodium level in hypernatremia?
P117
Guideline is <12 mEq/L per day
HYPERNATREMIA
What is the major complication of lowering the sodium
level too fast?
P117
Seizures (not central pontine myelinolysis)
HYPONATREMIA
What are the surgical causes of the following types:
Hypovolemic
P117
Diuretic excess, hypoaldosteronism, vomiting, NG suction, burns, pancreatitis, diaphoresis
HYPONATREMIA
What are the surgical causes of the following types:
Euvolemic
P118
SIADH, CNS abnormalities, drugs
HYPONATREMIA
What are the surgical causes of the following types:
Hypervolemic
P118
Renal failure, CHF, liver failure (cirrhosis), iatrogenic fluid overload (dilutional)
HYPONATREMIA
What are the signs/ symptoms?
P118
Seizures, coma, nausea, vomiting, ileus, lethargy, confusion, weakness
HYPONATREMIA
What is the treatment of the following types:
Hypovolemic
P118
NS IV, correct underlying cause
HYPONATREMIA
What is the treatment of the following types:
Euvolemic
P118
SIADH: furosemide and NS acutely, fluid restriction
HYPONATREMIA
What is the treatment of the following types:
Hypervolemic
P118
Dilutional: fluid restriction and diuretics
HYPONATREMIA
How fast should you increase the sodium level in
hyponatremia?
P118
Guideline is <12 mEq/L per day
HYPONATREMIA
What may occur if you correct hyponatremia too quickly?
P118
Central pontine myelinolysis!
HYPONATREMIA
What are the signs of central pontine myelinolysis?
P118
- Confusion
- Spastic quadriplegia
- Horizontal gaze paralysis
HYPONATREMIA
What is the most common cause of mild postoperative
hyponatremia?
P118
Fluid overload
HYPONATREMIA
How can the sodium level in SIADH be remembered?
P118
SIADH = Sodium Is Always Down Here = Hyponatremia
“PSEUDOHYPONATREMIA”
What is it?
P118
Spurious lab value of hyponatremia as a result of hyperglycemia, hyperlipidemia, or hyperproteinemia
HYPERCALCEMIA
What are the causes?
P119
“CHIMPANZEES”:
Calcium supplementation IV
Hyperparathyroidism (1° /3° ) hyperthyroidism
Immobility/Iatrogenic (thiazide diuretics)
Mets/Milk alkali syndrome
Paget’s disease (bone)
Addison’s disease/Acromegaly
Neoplasm (colon, lung, breast, prostate, multiple myeloma)
Zollinger-Ellison syndrome (as part of MEN I)
Excessive vitamin D
Excessive vitamin A
Sarcoid
HYPERCALCEMIA
What are the signs/ symptoms?
P119
Hypercalcemia—“Stones, bones, abdominal groans, and psychiatric overtones” Polydipsia, polyuria, constipation
HYPERCALCEMIA
What are the ECG findings?
P119
Short QT interval, prolonged PR interval
HYPERCALCEMIA
What is the acute treatment of hypercalcemic crisis?
P119
Volume expansion with NS, diuresis with furosemide (not thiazides)
HYPERCALCEMIA
What are other options for lowering Ca⁺ level?
P119
Steroids, calcitonin, bisphosphonates (pamidronate, etc.), mithramycin, dialysis (last resort)
HYPOCALCEMIA
How can the calcium level be determined with
hypoalbuminemia?
P119
(4-measured albumin level) x 0.8, then add this value to the measured calcium level
HYPOCALCEMIA
What are the surgical causes?
P119
Short bowel syndrome, intestinal bypass, vitamin D deficiency, sepsis, acute pancreatitis, osteoblastic metastasis, aminoglycosides, diuretics, renal failure,
hypomagnesemia, rhabdomyolysis
HYPOCALCEMIA
What is Chvostek’s sign?
P119
Facial muscle spasm with tapping of facial nerve (Think: CHvostek = CHeek)
HYPOCALCEMIA
What is Trousseau’s sign?
P120
Carpal spasm after occluding blood flow in forearm with blood pressure cuff
HYPOCALCEMIA
What are the signs/symptoms?
P120
Chvostek’s and Trousseau’s signs, perioral paraesthesia (early), increased deep tendon reflexes (late), confusion, abdominal cramps, laryngospasm, stridor, seizures, tetany, psychiatric abnormalities (e.g., paranoia, depression, hallucinations)
HYPOCALCEMIA
What are the ECG findings?
P120
Prolonged QT and ST interval (peaked T waves are also possible, as in hyperkalemia)
HYPOCALCEMIA
What is the acute treatment?
P120
Calcium gluconate IV
HYPOCALCEMIA
What is the chronic treatment?
P120
Calcium PO, vitamin D
HYPOCALCEMIA
What is the possible complication of infused calcium if the IV infiltrates?
P120
Tissue necrosis; never administer peripherally unless absolutely necessary (calcium gluconate is less toxic than
calcium chloride during an infiltration)
HYPOCALCEMIA
What is the best way to check the calcium level in the ICU?
P120
Check ionized calcium
HYPERMAGNESEMIA
What is the normal range for magnesium level?
P120
1.5–2.5 mEq/L
HYPERMAGNESEMIA
What is the surgical cause?
P120
TPN, renal failure, IV over supplementation
HYPERMAGNESEMIA
What are the signs/ symptoms?
P120
Respiratory failure, CNS depression, decreased deep tendon reflexes
HYPERMAGNESEMIA
What is the treatment?
P120
Calcium gluconate IV, insulin plus glucose, dialysis (similar to treatment of hyperkalemia), furosemide (Lasix)
HYPOMAGNESEMIA
What are the surgical causes?
P120
TPN, hypocalcemia, gastric suctioning, aminoglycosides, renal failure, diarrhea, vomiting
HYPOMAGNESEMIA
What are the signs/symptoms?
P121
Increased deep tendon reflexes, tetany, asterixis, tremor, Chvostek’s sign, ventricular ectopy, vertigo, tachycardia,
dysrhythmias
HYPOMAGNESEMIA
What is the acute treatment?
P121
MgSO4 IV
HYPOMAGNESEMIA
What is the chronic treatment?
P121
Magnesium oxide PO (side effect: diarrhea)
HYPOMAGNESEMIA
Hypomagnesemia may make it impossible to correct what other electrolyte abnormality?
P121
Hypokalemia (always fix hypomagnesemia with hypokalemia)
HYPERGLYCEMIA
What are the surgical causes?
P121
Diabetes (poor control), infection, stress, TPN, drugs, lab error, drawing over IV site, somatostatinoma, glucagonoma
HYPERGLYCEMIA
What are the signs/symptoms?
P121
Polyuria, hypovolemia, confusion/coma, polydipsia, ileus, DKA (Kussmaul breathing), abdominal pain, hyporeflexia
HYPERGLYCEMIA
What is the treatment?
P121
Insulin
HYPERGLYCEMIA
What is the Weiss protocol?
P121
Sliding scale insulin
HYPERGLYCEMIA
What is the goal glucose level in the ICU?
P121
80–110 mg/dL
HYPOGLYCEMIA
What are the surgical causes?
P121
Excess insulin, decreased caloric intake, insulinoma, drugs, liver failure, adrenal insufficiency, gastrojejunostomy
HYPOGLYCEMIA
What are the signs/ symptoms?
P121
Sympathetic response (diaphoresis, tachycardia, palpitations), confusion, coma, headache, diplopia, neurologic deficits, seizures
HYPOGLYCEMIA
What is the treatment?
P121
Glucose (IV or PO)
HYPOPHOSPHATEMIA
What is the normal range for phosphorus level?
P122
2.5–4.5 mg/dL
HYPOPHOSPHATEMIA
What are the signs/symptoms?
P122
Weakness, cardiomyopathy, neurologic dysfunction (e.g., ataxia), rhabdomyolysis, hemolysis, poor pressor response
HYPOPHOSPHATEMIA
What is a complication of severe hypophosphatemia?
P122
Respiratory failure
HYPOPHOSPHATEMIA
What are the causes?
P122
GI losses, inadequate supplementation, medications, sepsis, alcohol abuse, renal loss
HYPOPHOSPHATEMIA
What is the critical value?
P122
1.0 mg/dL
HYPOPHOSPHATEMIA
What is the treatment?
P122
Supplement with sodium phosphate or potassium phosphate IV (depending on potassium level)
HYPERPHOSPHATEMIA
What are the signs/symptoms?
P122
Calcification (ectopic), heart block
HYPERPHOSPHATEMIA
What are the causes?
P122
Renal failure, sepsis, chemotherapy,
hyperthyroidism
HYPERPHOSPHATEMIA
What is the treatment?
P122
Aluminum hydroxide (binds phosphate)
MISCELLANEOUS
This ECG pattern is consistent with which electrolyte abnormality?
P122 (picture)
Hyperkalemia: peaked T waves
MISCELLANEOUS
If hyperkalemia is left untreated, what can occur?
P123 (picture)
Ventricular tachycardia/fibrillation → death
MISCELLANEOUS
Which electrolyte is an inotrope?
P123
Calcium
MISCELLANEOUS
What are the major cardiac electrolytes?
P123
Potassium (dysrhythmias), magnesium
dysrhythmias), calcium (dysrhythmias/inotrope
MISCELLANEOUS
Which electrolyte must be monitored closely in patients on digitalis?
P123
Potassium
MISCELLANEOUS
What is the most common cause of electrolyte-mediated
ileus?
P123
Hypokalemia
MISCELLANEOUS
What is a colloid fluid?
P123
Protein-containing fluid (albumin)
MISCELLANEOUS
What is the rationale for using an albuminfurosemide
“sandwich”?
P123
Albumin will pull interstitial fluid into the intravascular space and the furosemide will then help excrete the fluid as urine
MISCELLANEOUS
An elderly patient goes into CHF (congestive heart failure) on POD #3 after a laparotomy. What is going on?
P123
Mobilization of the “third-space” fluid into the intravascular space, resulting in fluid overload and resultant CHF (but
also must rule out MI)
MISCELLANEOUS
What fluid is used to replace NGT (gastric) aspirate?
P123
D5 1/2 NS with 20 KCl
MISCELLANEOUS
What electrolyte is associated with succinycholine?
P123
Hyperkalemia