Fluid Therapy in Equine Patients Flashcards

1
Q

What are the 5 levels of dehyrdation? What is seen at each stage?

A
  • <5% = NSF
  • 5% = dry/tacky membranes, mild depression
  • 7% = moderate skin tent, tachycardia, slow jugular refill
  • 10% = moderate to marked skin tent, decreased pulse pressure, cold extremities, depressed
  • 12% = marked skin tent, signs of shock, obtundation
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2
Q

Estimating volume loss:

A

CRT not as sensitive in eqiune patients

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3
Q

What are the 3 goals of fluid therapy?

A
  1. restore intravascular volume
  2. improve tissue perfusion
  3. overcome regional circulatory deficiency
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4
Q

When is the emergency phase of fluid therapy recommended? What doses are used? In foals?

A

10-12% dehydration —> shock!

  • shock dose of 60-90 mL/kg
  • 1/4 to 1/3 dose and reasses
  • 10-20 L bolus

1L bolus

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5
Q

What is replacement fluid therapy? How is deficit volume calculated?

A

deficit + maintainence + continuing loss

% dehydration x BW (kg)

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6
Q

What maintaining fluids are used in adult and foals?

A

2-4 mL/kg/hr

3-5 mL/kg/hr (including oral!)

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7
Q

A 400 kg horse presents for diarrhea nad is assessed to be 8% dehydrated. What is the fluid deficit?

A

0.08 x 400 kg = 32 L fluids

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8
Q

What is the general 24-hour plan for approaching fluid therapy?

A
  • FIRST HOUR = fluid bolus to address shock
  • 3-4 HOURS = address replacement and ongoing loses with 50% deficit
  • NEXT 12 HOURS = address remaining deficit
  • REST = address maintenance and losses

monitor and reassess after 24 hours

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9
Q

A 400 kg horse presents for diarrhea nad is assessed to be 8% dehydrated. Make a fluid plan for this horse over the next 24 hours.

A

0.08 x 400 kg = 32 L fluids to address deficit

  • FIRST BOLUS OF 50% over 3 hours = 32L x 0.5 = 16 L
  • 16 L left to give over 12 hours = 16L/12hr = 2.3 L/hr
  • MAINTENANCE = 60 mL/kg/day x 400 kg = 24 L/day = 1 L/hr
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10
Q

What are the 3 most common sites for IV catheter locations in horses for fluids?

A
  1. jugular*
  2. lateral thoracic
  3. cephalic - hard to maintain large amounts of ongoing fluids

14 g IVC

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11
Q

What are the 2 types of IV catheters?

A
  1. over the needle - short, Abbocath (polyurethane made for short-term 24-48 hrs), Mila (polytetrafluoroethylene for long-term up to 14 days)
  2. over the wire - Sialastic = flexible, common in foals with 1-2 lumens
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12
Q

What type of extension set is recommended for IV fluids set up in horses?

A

larger bore —> too small = rate limiting

  • recommended to wrap in horses, older ones tend to leave them alone
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13
Q

What is the difference between administration and transfer sets?

A

ADMINISTRATION = “stat” set, has coil to allow movement of horse, attaches 2 bags

TRANSFER = connects up to 4 fluid bags

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14
Q

How are administration sets attached?

A
  • braided into horses mane
  • attached to catheter
  • hangs 2-4 5L bags = 10-20 L total
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15
Q

Crystalloid fluids, composition:

A
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16
Q

What 3 fluids are most commonly used for rehydration?

A
  1. Normosol-R
  2. Plasma-Lyte
  3. LRS (+maintenance)
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17
Q

What use does 0.9% NaCl have?

A
  • hyperkalemia
  • hyponatremia
  • hypochloremia
18
Q

What use does 0.45% NaCl and 2.5% dextrose have?

A
  • neonates
  • hypernatremia
19
Q

What use does 5% dextrose have?

A

water deficit

20
Q

What are the 3 most common uses of hypertonic saline?

A
  1. rapid, transient increase in blood volume - 4x normal dose, shorter duration (45 mins), depletes intracellular volume
  2. increase BP, and CO/O2 delivery
  3. decreased ischemic/reperfusion injury
21
Q

How can the intracellular fluid deficit caused by hypertonic fluid administration be corrected?

A

administer 10L of isotonic fluid per L of hypertonic fluid

22
Q

What 3 actions do colloids have? What are the 3 major indications?

A
  1. restores effective circulating volume
  2. supports oncotic pressure (albumin!)
  3. expands plasma volume
  • TP < 4 mg/dL
  • albumin < 3 mg/dL
  • COP < 12 mmHg
23
Q

What is the purpose of administering plasma? How is it used?

A

source of albumin and clotting factors (COP = 20 mmHg)

10 L plasma required to increase TP by 1.0 g/dL

24
Q

How is the amount of plasma to be administered calculated?

A

0.05 x BW x ([desired TP - patient TP]/donor TP)

25
What are some synthetic colloids? What 2 actions does it have? What does it not affect?
hetastarch or pentastarch 6% solution in isotonic saline (COP = 30-37 mmHg) 1. increases vascular space (by 141%) for 12-48 hrs 2. increases COP TP does not increase
26
What dose of synthetic colloids are recommended? In what situations are they used?
10-20 mL/kg - platelet dysfunction - renal injury
27
What clinical signs should be observed with successful fluid therapy?
- HR normalization - increased pulse quality - improved mentation - decreased CRT - increased urine production - warming extremities
28
What lab work should be monitored with fluid therapy?
- PCV/TS - USG (neonates) - blood serum lactate - indicative of oxygen consumption by tissue and perfusion (< 2 mmol/L) - electrolytes - fluids are not complete (especially if on fluid for > 24 hrs)
29
How important are electrolyte disturbances in fluid therapy? What are the 2 most important disturbances that should be corrected?
unless severe deficit, not crucial part of therapy 1. hypocalcemia - cantharidin toxicity, thumps 2. hypoglycemia - septicemia, NMS in foals
30
What are the 3 major actions of calcium?
1. skeletal muscle contraction 2. neuronal function 3. GI smooth muscle function
31
What are 4 causes of hypocalcemia? How is it treated?
1. endotoxemia 2. functional SI disturbances 3. common in endurance horses 4. postpartum dairy cattle 50-100 mL or 500 mL 23% calcium gluconate
32
What is the normal distribution of potassium? What are the 2 most common signs of hypokalemia? How is it treated?
<2% in ECF (mostly intracellular) ---> extracellular shift possible 1. reduced intestinal motility 2. muscle weakness, lethargy 0.5 mEq/kg/hr or 10-20 mEq/L = 50-100 mEq/5 L bag
33
How should sodium levels be altered? Why?
SLOW ---> can cause cerebral edema with rapid decrease or osmotic demyelination with rapid increase < 0.5 mEq/L/hr or 8-12 mEq/day
34
What are the most common causes of hypernatremia? How is it treated?
- prolonged fluid administration - water deprivation 0.45% NaCl + 5% dextrose
35
What are the most common causes of hyponatremia? How is it treated?
- profound colitis - sepsis polyionic fluid with 3% NaCl
36
What are the 4 most common causes of hypochloremia? How is it treated?
1. GI loss or sequestration 2. metabolic acidosis 3. hyperkalemia 4. hyponatremia 0.9% NaCl
37
What are 4 indications for administering dextrose? What treatment plan is used?
1. early lactation ketosis 2. nutritional support in foals 3. uroperitoneum in foals 4. urolithiasis in farm animals (not commonly an issue in adults) 2.5-10% solution in CRI - 100 mL 50% dextrose/1 L = 5% solution
38
You need to make a 2.5% dextrose solution in a 5 L bag using 50% dextrose as the stock solution. How much 50% dextrose do you add to the bag?
39
What are the 3 major indications for enteral fluid therapy?
1. functional GIT 2. maintenance requirements needed 3. impaction colic
40
What are 4 advantages of enteral fluid therapy?
1. fluid directly into GIT 2. stimulates colonic motility 3. decreased expense 4. decreased need for precise adjustment
41
What equipment is used for enteral fluid therapy? When are indwelling feeding tubes set up?
- nasogastric intubation (2-6 L/dose) - funnel - electrolyte powder, isotonic electrolyte solution - coil set - carboy providing constant administration of fluid 2-5 L/hr