Fluid & Electolytes / Nutrition Flashcards
Weight gain per day calculation
difference in weight / current weight / number of days
preterm infant: 15-20g/kg/day
Plasma Triglyceride levels should be measured with each ______ in _________; a serum triglyceride level less than _____ indicates lipid tolerance.
w/ each increased in lipids
should be <200
decreased _________ and __________ or increased ____________ are indicators of bone demineralization
decreased calcium and phosphorous levels or increased alk-phos levels
Alk-Phos Levels indicative of bone demineralization
levels greater than 500 mg/dL
Serum Phosphorous level indicative of bone demineralization
<4 mg/dL
Estimated Endogenous glucose production
4mg/kg/day
Appropriate GIR for term infant
4-5 mg/kg/min
Appropriate GIR for Preterm Infant
6-10 mg/kg/min
1 gram of dextrose is _____ kcal
3.4 kcal
Breastfed infants require slightly _____ caloric requirement due to the amount of energy required to metabolize formula
less
Mature human milk has _____ g of protein per 100mL
0.9g of protein per 100mL
Term Protein Requirements (Enteral and Parenteral)
Enteral: 2 - 2.5g/kg/day
Parenteral: 1.5-2.5g/kg/day
Term Lipid Requirements (Parenteral and enteral)
Parenteral: 2-4 g/kg/day
Enteral: 3-4 g/kg/day
Term Calorie Requirements (same for enteral and parenteral)
100-120 kcal/kg/day
Term Fluid Requirements
Parenteral: 100-120 ml/kg/day
Enteral: 120-150 ml/kg/day
Preterm Fluid Requirement (parenteral and enteral)
parenteral : 120 to 150 ml/kg/day
enteral: 150-200 mg/kg/day
Preterm Caloric requirement (parenteral and enteral)
Parenteral requirements 80-100 kcal/kg/day (goal calories for extreme premature infants on full PN 90-100kcal/kg/day)
Preterm infants on parenteral nutrition have a slightly lower caloric requirement than enteral feeds due to lower activity levels and fecal losses
Preterm Protein Requirements
Preterm infants less than 30 weeks - 3.5g/kg/day
The use of larger fluid volumes in a preterm infant increases the risk of _________.
PDA, cerebral IVH, BPD, and NEC
Mature human milk has ____ g of fat per 100 mL.
3.5g of fat per 100 mL
Neonatal Amino Acid solutions have a _______ pH allowing for greater concentrations of ________ and __________.
lower pH allowing for greater concentrations of phosphorous and calcium
purpose of acetate in PN
aids with correction of hyperchloremic metabolic acidosis
Addition of chloride to PN
aids with correction of metabolic alkalosis
addition of cysteine to PN
improves the calcium and phosphorous solubility by lowering the pH
PN recommendations for infants with impaired biliary excretion or liver function
omit copper and manganese
Peripherally infused PN should not exceed an osmolality of _____
900 mOsm/L (which can limit carb and AA delivery)
Recommended vitamin D supplementation for term and preterm infants
400mg
IV Lipids can displace __________ from binding sites on ___________ therefore should be used in caution in patients with significant _______________.
IV Fats displace bilirubin from binding sites on albumin ; use cautiously in patients with hyperbilirubenemia
Enteral protein sources include ______ and ______
whey and casein
Preterm infant enteral carbohydrate requirement
8 to 12g/kg/day
Optimal Feeding tube size
infants <1000g require a 5 french
>1000g - #6-8 french
Caloric density can be advanced from 20kcal/oz to 24 kcal/oz in preterm infants when the feeding volume reaches ________
100ml/kg/d
Preterm maternal milk in comparison to term maternal milk
preterm milk is higher in cholesterol, phospholipids, and very long chain PUFAs than term milk
Preterm milk has higher sodium content chloride levels
as lactation progresses, total fat content increases and cholesterol and phospholipid content decreases.
Changes in whey:Casein ratio as lactation progresses
The whey casein ratio changes from 80:20 at the start of lactation to 55:45 in mature milk
whey decreases and casein increases as lactation progresses
leading whey protein in human milk
∝lactoferrin which is high in AA
Mature milk has a fat content of _____g/dL
4-5g/dL
primary component of human milk fat
Triglycerides
Primary carbohydrate in human milk
lactose
Preterm formulas are ______ predominant
whey
soy protein formulas are not recommended due to….
their low calcium and phosphorous content (increased risk of developing ostopenia of prematurity)
Formula for Cystic Fibrosis AND/OR hepatic insufficiency
semi-elemental formula containing reduced LCTs w/ supplemented MCT OR standard formula with pancreatic enzyme supplementation
due to impaired digestion and absorption of long-chain fats
Formula for galactosemia
soy protein-based formula b/c it is lactose free
Formula for lactose intolerance
low lactose formula
formula for lymphatic anomalies
significantly reduced LCT with supplemented MCT
Formula for NEC
preterm formula or semi-elemental formula if indicated r/t impaired digestion
Formula for renal insufficiency
standard formula
Fat soluble vitamins
vitamins A, D, E, K
Water Soluble vitamins
vitamin c and B
Vitamin A in milk
colostrum contains the highest amounts of vitamin A
vitamin a content in preterm and term milk are equal but decrease as milk matures
Improving vitamin A levels in the preterm infant decreases incidences of _______ or ______.
Chronic Lung Disease or BPD
Iron Supplementation
should receive at 2-4 weeks of age; infants receiving an erythrocyte stimulating agent require hire dosing
Nutritional Considerations for BPD
fluid restriction with increased metabolic demand (must increase caloric density to meet caloric needs while restricting total fluid)
ECG changes with Hypocalcemia
prolonged ST and QT
ECG changes with hypokalemia
Depressed ST, flat or inverted T, Prominent U wave
ECG changes with hypercalcemia
shortened ST, wide T
ECG changes with hyperkalemia
tall, peaked T waves, Flat P waves, wide QRS
ECG changes with hypomagnesia
tall T, depressed ST
ECG changes with hypermagnesia
long PR, Wide QRS
Fetal swallowing of amniotic fluid starts by ________
8-11 weeks
goals for length and head circumference
1 cm/week
Subobtimal head circumference has an association with ______
higher neurodevopmental risk
Kcals in 1 gram of protein
4kcal
kcal in 20% lipid emulsion solution
2kcal/mL or 10kcal/gram
kcal in 1 gram dextrose
3.4
impaired biliary excretion - limit _______ in tpn
copper and manganese
vitamin D is known to prevent __________; Dose _______
osteopenia, 400 IU per day
Iron Dosing needs to be higher in __________
infants receiving an erythrocyte-stimulating agent such as erythropoietin
Infants born to diabetic mothers often present with transient _________
hypomagnesia
oxytocin and maternal diuretic use may result in fetal and maternal __________
hyponatremia
Antenatal steroids can enhance lung maturation and skin maturation which decreases _________ and reduces risk of ___________.
decreases IWL, and reduces risk of hyperkalemia
Severe hypoxia or asphyxia at birth can lead to __________________, requiring a lower ______________.
can lead to renal tubular necrosis, requiring a lower TFG
Fractional excretion of sodium - definition and calculation
reflects balance between GFR and tubular reabsorption of Na+
calculated:
FENa = (urine sodium x plasma Cr) / (plasma Na x urine Cr) x 100
Treatment of edema
Na+ restriction and/or fluid restriction in cases of low serum sodium
Normal sodium requirements
2-4 meq/kg/day or greater with renal Na+ losses from renal immaturity
Hyponatremia r/t ECF volume depletion symptoms
tachycardia, rising BUN, metabolic acidosis.
Sodium deficit calculation
Sodium defecit = (sodium desired - actual serum sodium) x 0.6 x weight (kg)
Hyponatremia with normal ECF volume
can result from excess fluid admin; If sodium >120, restrict fluids. If sodium <120, diuretics
Hyperlipidemia can cause a fictitiously low ________
serum sodium
Hypernatremia Differential (3)
- Excess Na intake
- Drug induced (albumin, NaHCO3, Antibiotics)
- Hypovolemia
Hyponatremia Differential (5)
- Inadequate intake
- SIADH ( increased weight, low urine output, high urine osmo)
- Drug induced
- Volume Overload (increased weight, high urine output, low urine osmo)
- False low
Symptomatic Hyponatemia with seizures for Na <120, treatment
Hypertonic NaCl (3) 6ml/kg over 1-2 hours
Hyperkalemia Differential (5)
- False high
- increased intake
- Endogenous K+ release
- Ionic Shifts
- Impaired excretion
Hyperkalemia with EKG changes treatment
- Calcium gluconate
- Sodium Bicarb
- Insulin / Glucose push / drip
Hyperkalemia without EKG changes treatment
- stop K+ admin
- adequate fluid intake
- Consider lasix
- Keep calcium in normal-high levels
Hypokalemia Differential (3)
- Decrease Intake / GI Losses ( i.e. NEC)
- Renal Losses
- Ionic shift (insulin, metabolic alkalosis, meds, hypothermia)
How does insulin decrease potassium levels
enhances intracellular uptake of K+ by stimulating the membrane-bound NA-K ATPase. (MUST ALWAYS ACCOMPANY WITH GLUCOSE TO MAINTAIN GLUCOSE LEVELS)
Respiratory Acidosis causes
inadequate alveolar ventilation, leading to an excess of CO2 and decrease in pH
Respiratory Alkalosis causes
r/t alveolar hyperventilation, leading to a decrease in CO2 and increase in pH. f
Metabolic acidosis causes
r/t an excess of acid in the ECF or a loss of buffer, leading to a decrease in pH. Conditions such as hypoxia, immature renal tubular function, or diarrhea; The presence of anion gap helps to differ between conditions
Metabolic alkalosis
vomiting or diarrhea, or continuous gastric suction can induce (acid losses)
Metabolic acidosis in presence of anion gap (>15)
acute renal failure, inborn error of metabolism, lactic acidosis, toxins
IWL calculation
Fluid intake - urine output + weight change