Fluid and Electrolytes (A&P Review) Flashcards
What are electrolytes?
Molecules that split into ion when in water.
What are the electrolytes that are cations (positively charged)?
- Na
- K
- Ca
- Mg
What are the electrolytes that are anions (negatively charged?)
- HCO3 (bicarbonate)
- CL (chloride)
- PO4 (phosphate/phosphorus)
What electrolytes are most present in ICF?
- K
- PO4
- Mg
What electrolytes are most prevalent in ECF?
- Na
- Cl
Fluid Spacing
- First Spacing: fluid is normal (everything is where it’s supposed to be)
- Second spacing: increased fluid in interstitial spaces
- Third spacing: fluid in areas that normally has little to no fluid in it (ex, ascites aka fluid in the abdomen, fluid in the lungs)
Unit of Electrolytes
mEq = milliequivalents
How is fluid intake regulated?
- Thirst
- Plasma osmolality
- Decrease in blood volume
How does fluid output occur?
Through skin, kidneys, lungs, and GI tract
- Fluid loss through skin and lungs is called insensible loss as you can’t measure how much water comes out of your skin and lungs like you can from your kidneys and GI tract
ADH
- Hormone that helps regulate homeostasis of fluid balance
- Plasma osmolality increases, then ADH released, causing kidneys to reabsorb water, leading to plasma volume increasing and plasma osmolality decreasing
- ADH inhibited by normal osmolality
Renin
- Hormone that helps regulate homeostasis of fluid balance
- Important in the regulation of BP.
- Made and secreted by the kidneys
- Released into the bloodstream in response to decreased renal perfusion, decreased BP, decreased eCF, decreased serum Na+ concentration, and increased urinary Na+ concentration.
- Elevated BP inhibits renin release
Aldosterone
- Hormone that helps regulate homeostasis of fluid balance
- maintains ECF volume by promoting renal reabsorption of Na+ and excreting of K+ and hydrogen ions.
- stimulated by hyponatremia, hyperkalemia, and angiostensin II
- inhibited by ANP and hypokalemia
Dehydration
- type of FVD
- deficit of water in the ECF
Isotonic Dehydration/ Hypovolemia
- type of FVD
- caused by decrease in plasma volume while the serum osmolality of the blood remains unchanged
- most common type of FVD (80% of FVD cases)
Hypertonic Dehydration
- type of FVD
- caused primarily by loss of water
- water loss exceeds sodium loss making blood hypertonic to normal body fluids
Hypotonic Dehydration
- type of FVD
- caused by loss of water and sodium
- more sodium than water is lost, making blood hypotonic to normal body fluids
Causes of Isotonic Dehydration
- Hemorrhage
- Diarrhea
- Emesis
- Suctioning
- Profuse Sweating
- Drainage
- Diuretic Therapy
- Severe Burns
- CO poisoning