Fluid And Electrolyte Balance Flashcards
Intracellular fluid
- Is 2/3 of total body fluid.
- essential for cell metabolism
- Primary cations in ICF are potassium and magnesium
- primary anions are phosphate and sulfate
Difference between anion and cation
Anion- negative charge
Cation- positive charge
Extracellular fluid
1/3 total body fluid
Transports nutrients to cells
Transports waste to kidneys or other disposal.
Consists of intravascular fluid (in vessels)
And interstitial fluid (between cells and blood vessels)
In GI and lymph systems.
Primary cation- sodium,
Primary anion- bicarbonate and chloride
Diffusion
Movement of fluids and electrolytes from an area of high concentration to low concentration.
Example is the movement of oxygen from alveoli into pulmonary blood vessels.
Filtration
Movement of fluid and electrolytes from areas of high pressure to areas of low pressure based on the mechanism of hydrostatic pressure.
Movement of blood from capillaries into interstitial fluid is an example of hydrostatic pressure.
Main element responsible for ensuring acid-base balance.
Hydrogen
Hydrogen ion concentration
If hydrogen ion concentration is lower than neutral the pH values will be higher than neutron.
Low hydrogen= then pH is alkaline, higher than 7.
High hydrogen= then pH is acid, lower than 7.
Buffer
Anything that either binds (absorbs) or releases hydrogen ions.
Buffers stabilize hydrogen ion concentration by neutralizing strong acids or alkalis(bases).
Normal pH of body fluids
7.35- 7.45
How do lungs maintain acid-base balance?
Normal respiration eliminates carbon dioxide.
Carbon dioxide can contribute to acidosis if it accumulates in the blood as carbonic acid.
How do kidneys maintain acid-base balance?
Kidneys are primary regulator of overall fluid and electrolyte balance in the body.
Kidneys either excrete hydrogen and/or bicarbonate ions in urine or by reabsorbing these ions.
Primary hormones that influence urinary output and fluid balance (2)
Aldosterone and
anti-diuretic hormone (ADH)
ADH plays Important role in fluid reabsorption into the blood.
Sodium (Na+)
Primary cation and extracellular fluid.
Maintains fluid balance.
Sodium aids in muscle contraction and transmission of nerve impulses to the muscles.
Aldosterone
Steroid hormone secreted by the adrenal gland.
Helps to maintain sodium balance and potassium balance
Regulates chloride
Potassium (K+)
Primary cation in intracellular fluid.
Responsible for overall muscle contraction, cardiac muscle contraction in particular and impulse transmission of nerves.
Calcium (Ca2+)
Cation
Most plentiful electrolyte in the body. Important for bone into the formation, muscle contraction and relaxation, impulse conduction in the heart, and clotting of blood.
Magnesium (M2+)
Cation in intracellular fluid.
Helps to regulate the heart, promotes neuromuscular and metabolic functioning, component of bones.
kidneys help regulate magnesium
Chloride (Cl-)
Most plentiful anion in extracellular fluid.
Regulated by kidneys and aldosterone secretion.
Gastric juice in the stomach is composed largely of chloride in the form of hydrochloric acid.
Bicarbonate (HCO2-)
Present in both fluid compartments intra-and extra cellular.
Considered a base or alkaline buffer and aids in regulating acid-base balance.
Not ingested in food but is continually produced by the body through various metabolic processes
Phosphate (HPO4 2-)
Most plentiful intracellular anion. A buffer.
Phosphate is important to the formation of bones and teeth; carbohydrate protein and fat metabolism; neuromuscular activity; acid-base balance and calcium regulation
regulated by kidneys and parathyroid hormone
Normal sodium value
135-146 meq/ l
Potassium lab value range
3.5-5.3 meq/l
Over 7 is dangerous
Calcium lab value range
8.5- 10.5 mg/dL total serum Ca
Magnesium normal lab value range
1.5 -2.5 milliequivalents per liter
Chloride normal lab value range
98-108 meq/L
Bicarbonate normal lab value range
22-26 meq/ L
Arterial blood
Phosphate normal lab value range
0.8- 1.5
How to tell if infant is dehydrated
Anterior fontanelle is depressed.
Hypovolemia
(Fluid volume deficit)
What would test results look like for hypovolemia?
Elevated hematocrit Elevated BUN High sp. gravity of urine: >1.030 Elevated serum sodium and chloride Decreased central venous pressure (CVP) Decreased urine volume <30ml/hr
Signs and symptoms of hypovolemia.
Weakness, low temp, weight loss Dry mucous membranes, confusion and slurring of speech, tachycardia, hypotension, orthostatic hypotension, flat neck veins oliguria
Hypervolemia
(Fluid volume excess)
What do you lab values look like?
Decreased hematocrit
Serum sodium: usually unchanged or decreased
Urine: Low specific gravity <1.010
Increased central venous pressure (CVP)
Signs and symptoms of hypervolemia
Weight gain, pitting Edema in legs or sacrum, lethargy, confusion, Rales dyspneic, hypertension distended neck veins
Pitting edema measurement
1+= 2mm indentation 2+= 4mm 3+= 6mm 4+= 8mm
Ascites
Accumulation of fluid in peritoneal cavity of abdomen.
Usually seen in severe liver disease and low albumin levels.
Can also be caused by cancers of colon, endometrium, pancreas, ovaries, and liver.
Extracellular Fluid shift or third space syndrome
Excess fluid and body between Intravascular and interstitial spaces.
Can be caused by injuries like sprains, burns or abdominal surgery.
Causes of Hyponatremia
“NO NA”
Na+ excretion increased with renal problems, NG suction, hypotonic fluids,
Overload of fluids with CHF, hypotonic solution, renal failure (dilutes sodium)
Na+ intake low or NPO
Antidiuretic hormone over secreted -SIADH (syndrome of inappropriate antidiuretic hormone - retains water and dilutes sodium)
Symptoms of hyponatremia
“SALT LOSS”
Seizures and stupor
Abdominal cramping, Attitude changes(confusion)
Lethargic
Tendon reflexes diminished, Trouble concentrating
Loss of urine, Loss of appetite
Orthostatic hypotension, overactive bowel sounds
Shallow respiration (happens late due to muscle weakness)
Spasms of muscle
Causes of hypernatremia
“HIGH SALT”
Hypercortisolism (Cushing’s), hyperventilation
Increased intake of sodium (oral or IV)
GI tube feeding without adequate water supplement
Hypertonic solutions
Sodium retention, corticosteroids
Aldosterone overproduction (hyperaldosteronism)
Loss of fluids- infection,fever,sweating,diarrhea,diabetes insipidus
Thirst impairment
Symptoms of hypernatremia
“FRIED”
Fever,flushed skin Restless, really agitated Increased fluid retention Edema, extremely confused Decreased urine output
Causes of Hypokalemia
“DITCH” (your body trying to ditch potassium)
Drugs: laxatives, diuretics, corticosteroids
Inadequate consumption of K+ (NPO, anorexia)
Too much water intake - dilutes potassium
Cushing’ syndrome (retains sodium and water but wastes potassium)
Heavy Fluid Loss (NG suction, vomiting, diarrhea, wound drainage, sweating)
Symptoms of hypokalemia
Seven Ls
Lethargy and confusion Low shallow respirations Lethal cardiac dysrythmias Lots of urine Leg cramps Limp muscles Low BP and pulse
Causes of hyperkalemia
The body “CARED” too much about potassium.
Cellular movement of K+ from intra to extracellular (burns,tissue damage,acidosis)
Adrenal insufficiency with Addison’s disease
Renal failure
Excessive potassium intake
Drugs- triamterene, ACE inhibitors, NSAIDS, potassium sparing diuretic like spironolactone,