FLUID AND ELECTROLYTE Flashcards
Approx. ____ of body weight consists of fluid
60%
FACTORS - body fluids
AGE
GENDER
BODY FAT
Fluid Compartments:
Extracellular Fluid
Intracellular Fluid
Under Extracellular Fluid
Intravascular
Interstitial Fluid
Transcellular Space
ECF total body fluid
1/3
ICF total body fluid
2/3
Fluid that surrounds the cell
Contains 11 L to 12 L in adults
Lymph fluid
Interstitial Fluid
Smallest division of ECF
Contains approx. 1 L
Transcellular space
Plasma, effective circulating volume
3L of the 6L of blood volume in adults made up the plasma
Found within the blood vessel
Intravascular
MAJOR CATIONS (body fluid):
Sodium (Na+), Potassium (K+) ✓ Calcium (Ca+), Magnesium
(Mg+) ✓ Hydrogen ions (H+)
Loss of ECF into a space that does not contribute to the equilibrium between the ICF and ECF is referred to as
third-space fluid shift or third spacing.
MAJOR ANIONS
✓ Chloride (CI-), Bicarbonate (HCO3-)
✓ Phosphate (PO4-), Sulfate
(SO4-)
✓ Proteinate ions
- dominates the ECF. It is important in regulating the volume fluid of the body.
Sodium ions
-dominates the ICF.
Potassium
-the diffusion of water caused by a fluid concentration gradient.
Osmosis
- is the ability of all solutes to cause an osmotic force that promotes water movement from one compartment to another.
Tonicity
- the pressure exerted by the fluid on the walls of the blood vessel.
Hydrostatic pressure
- is the amount of hydrostatic pressure needed to step the flow of water by osmosis.
Osmotic pressure
- is the osmotic pressure exerted by proteins.
Oncotic pressure
- is the increase in urine output caused by excretion of substances such as glucose, mannitol, or contrast agents in the urine
Osmotic diuresis
- to move from an area of higher concentration to one of lower concentration
DIFFUSION
-movement of water and solutes occurs from an area of high hydrostatic pressure to an area of low hydrostatic pressure
FILTRATION
cell membrane, actively moves the sodium from I the cell into the ECF
Na-K pump (sodium potassium pump)
- implies that energy must be expended for the movement to occur against a concentration gradient
Active transport
Systemic routes of gains and losses
KIDNEYS
SKIN
LUNGS
GI
KIDNEYS-daily urine output in the adult is
1L to 2L approx.
sensible perspiration refers to visible water and electrolyte loss through skin
sweating
Fluid losses from the skin and lungs are referred to as _____ because they can’t be measured or seen.
insensible losses
Fluid losses from urination, defecation, wounds, and other means are referred to as ___ because they can be measured.
sensible losses
NORMAL VALUE
k
mg
na
ca
Inorganic phosphorus
phosphate
chloride
HCO3
3.5-5 mEq/L (ABG)
1.5-2 mEq/L
135-145 mEq/L
8.5-10.5 mEq/L
1-1.5 mmol/L (acid base value)
0.8-1.5 mmol/L
95-106 mmol/L
18.22 mmol/L
22-28 mEq/L
Osmolality measures in
Osmolarity
milliosmoles per kg of water
milliosmoles per liter
occurs when the loss of ECF volume exceeds the intake of fluid.
It occurs when water and electrolytes are lost in the same proportion as they exist in normal body fluids;
hypovolemia
results from loss of body fluids and occurs more rapidly when coupled with decreased fluid intake.
can also develop with a prolonged period of inadequate intake.
FVD (FLUID VOLUME DISTURBANCE)
first line choice for hypotensive patient with FVD
Isotonic solution
Fluid volume excess
An isotonic expansion of the ECF caused by an abnormal retention of water and sodium
HYPERVOLEMIA
Most abundant electrolyte in the ECF.
Primarily determinant of ECF volume and osmolality
Major role in controlling water distribution throughout the body
sodium
Serum sodium level that is less than 135 mEq/L (135 mmol/L)
Hyponatremia