flow and filtration Flashcards
filtration pressure: explain net filtration pressure (hydrostatic and oncotic pressures), explain how net filtration pressure may be affected by changes to either of these components (including arterial blood pressure, plasma protein concentration and ureteral obstruction)
what does net ultrafiltration pressure equal
hydrostatic pressure in glomerular capillaries - hydrostatic pressure of tubule - oncotic pressure of glomerular capillaries
what is the normal net ultrafiltration pressure
120 mmHg
what is the glomerular filtration rate equal to
net ultrafiltration pressure x ultrafiltration coefficient
what determines ultrafiltration coefficient
membrane permeability and SA available for filtration
how does a severe haemorrhage affect net ultrafiltration presure
reduce cardiac output, lowering driving force, decreasing net ultrafiltration pressure
how does an obstruction in nephron tubule affect net ultrafiltration pressure
opposing pressures elevated, decreasing net ultrafiltration pressure
how does a reduced plasma protein concentration affect net ultrafiltration pressure
opposing pressures decrease, increasing net ultrafiltration rate