Flavi Flashcards

1
Q

Serological cross reactions frequently occur between related flaviviruses

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2
Q

Many of the flaviviruses are zoonotic agents

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3
Q

Viruses of the Pestivirus genus are more resistant in the environment than the members of the Flavivirus genus

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4
Q

Viruses of the Pestivirus genus are more resistant in the environment than the other members of the Flavivirus genus

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5
Q

Yellow fever virus and Dengue virus are human pathogens

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6
Q

Louping ill is most frequently seen in sheep

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7
Q

Differential diagnoses of Louping-Ill: Listeria, Rabies, Scrapie

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8
Q

The tick borne encephalitis is endemic in central Europe

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9
Q

The tick borne encephalitis virus can be transmitted via consumption of raw milk

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10
Q

The consumption of raw goat milk is a possible source of human tick borne encephalitis

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11
Q

Biphasic fever is a characteristic of TBE

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12
Q

Consumption of contaminated, raw goat milk is a possible source of human tick-borne encephalitis virus infection

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13
Q

Inactivated vaccines are used for the prevention of humans from tick-borne encephalitis

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14
Q

Inactivated vaccines are available against tick-borne encephalitis for humans

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15
Q

Tick-borne encephalomyelitis mainly occurs clinically in humans

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16
Q

Tick-borne encephalomyelitis occurs throughout Europe and Asia

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17
Q

Tick-borne encephalomyelitis exists as natural foci infections

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18
Q

Occasionally tick-borne encephalomyelitis virus can be transmitted to humans via consuming raw milk

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19
Q

Tick-borne encephalomyelitis occurs seasonally

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20
Q

For humans inactivated tick-borne encephalomyelitis virus vaccines are also available

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21
Q

Migratory birds play a role in the transmission of West Nile virus

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22
Q

Mammals are mostly accidental hosts of West Nile Fever virus

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23
Q

West Nile Fever is a notifiable disease

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24
Q

In West Nile epidemics wild bird mortality is usually observed before horse and human cases can be detected

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25
To prevent West Nile Fever, vaccine is available for horses
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26
The West Nile virus may cause encephalitis in humans and in horses
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Horses and humans do not play a significant role in the transmission of West Nile virus
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The West Nile fever epidemics occur usually at the end of summer and during Autumn
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Wild birds are the natural hosts of West Nile virus
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Vaccines are available for the prevention of horses from WNV infections
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Different genetic lineages of West Nile virus are circulating in Europe
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Various strains of WNV, belonging to different genetic lineages are circulating in Europe
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There is no vaccine available for humans against WNV infection yet
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34
Mosquitoes are the principle vectors of the WNV
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The sero-diagnostics of WNV is complicated by cross-reactions with related flaviviruses
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Certain predatory bird species are particularly sensitive to WNV infections
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The use of repellents may reduce the risk of infection with WNV
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The weather influences the emergence of West Nile Virus outbreaks, through its effect on mosquito propagation dynamics
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Laboratory diagnosis should confirm the aetiology of West Nile encephalitis
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The most important maintaining hosts of West Nile fever virus are water birds
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Clinical signs of West Nile fever are most frequently seen in birds, horses and humans
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Neurological signs develop only in a small percentage of the diseased animals
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West Nile fever occurs worldwide
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Vectors of West Nile fever virus are different mosquito species
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The host range of West Nile virus is very wide
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The sero-diagnostics of West Nile virus is complicated by cross-reactions with related flaviviruses
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47
The Japanese encephalitis virus causes abortion in swine
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48
The yellow fever virus causes liver damages
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49
The zika virus causes fever, rash and conjunctivitis in humans
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50
BVDV can be frequently detected in the background of respiratory diseases
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51
In utero infection with non-cytopathic BVDV can cause seropositivity of the newborn calf
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In utero infection with non cytopathic BVDV can cause immunotolerance
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53
Two serotypes of the BVD virus are known so far, serotype 2 is more virulent
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Pigs infected with BVDV turn seropositive to classical swine fever
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Persistently infected cattle can maintain BVDV in a farm
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Non-cytopathic BVD virus strain can mutate and become cytopathic
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The BVD virus can infect pigs also
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58
Cytopathic strains of the Bovine Viral Diarrhoea virus (BVDV) can cause abortion
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Cattle which are immune tolerant to BVD virus may develop mucosal disease
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60
In sheep BVDV causes symptoms similar to border disease
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Mucosal disease can develop in cattle persistently infected with BVDV
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Non cytopathic strains of Bovine viral diarrhoea virus (BVDV) can cause immunosuppression
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Non cytopathic strains of Bovine viral diarrhoea virus (BVDV) can cause immunosuppression
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64
BVDV can be transmitted by semen
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65
In mucosal disease sharp edged, usually round or oval ulcers can be observed on the oral mucosa
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66
In mucosal disease haemorrhages can be observed under the serosal surfaces and in the kidney cortex
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67
Bloody diarrhoea is a clinical sign of the mucosal disease
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68
BVD and mucosal disease are caused by the same viral species
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Eradication programmes against the bovine viral diarrhoea virus are usually based on the selection of immunotolerant animals
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Eradication of BVD virus is based on the removal of immunotolerant animals
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Two genotypes of the BVDV are known
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BVDV forms one serotype, but there are significant antigenic differences between the strains
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Persistently infected animals play the major role in the maintenance and spread of BVDV
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BVDV infection may cause immunosuppression
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The BVD virus typically damages endothelial-, epithelial- and lymphatic tissues
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BVD clinically is mostly seen in cattle from 6 to 24 months of age
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BVD virus can cause severe damage to fetuses in pregnant cows
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BVD infection of pregnant cows can result in delivery of immunotolerant persistently infected calves
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Bulls can shed BVD virus for long time in semen, without showing any clinical sign
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Both attenuated live and inactivated vaccines are used in eradication of BVD
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BVDV is practically sensitive to disinfectants
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Cytopathic BVDV strains cause mucosal disease in immune-tolerant calves
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Goats can be infected with border disease
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84
In utero border disease virus infection may cause immunotolerance
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Border disease of sheep is mainly characterized by foetal damages
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Border disease appears as foetal damage in pregnant ewes
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Border disease occurs in Hungary
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Border disease causes abortion in ewes
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Border disease of sheep can be controlled by screening for carriers
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90
Haemorrhagic enteritis is a characteristic pathological lesion of Classical swine fever T Classical Swine Fever is frequently complicated with bacterial infections. T Classical swine fever virus can be transmitted by raw pork products T Classical swine fever virus can retain its infectivity for 6 months in frozen meat T The CSFV may survive in frozen meat for months T During necropsy enlarged bloody lymph nodes can be seen in Classical swine fever cases T Because of endothelial damage Classical swine fever results in haemorrhages T In acute Classical swine fever, at the beginning obstipation, later diarrhoea can be observed T Classical swine fever targets the bone marrow stem cells T Erysipelas and Porcine circovirus 2 infections may cause clinical signs and pathology lesions similar to CSF T Weakness of the hind legs and ataxia are clinical signs of Classical Swine Fever T Ischaemic infarcts at the edges of the spleen are postmortem lesions of subacute Classical Swine Fever T The boutons in the intestines are characteristic lesions in subacute Classical Swine Fever T Kidney haemorrhage is a characteristic lesion of Classical Swine Fever T Hemorrhages are the most typical lesions of acute CSF T During necropsy of acute Classical swine fever cases, haemorrhages can be seen in the gastric mucosa T Among Classical Swine Fever clinical signs CNS and eye problems can be observed
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Classical swine fever infection during the first half of pregnancy results in the birth of immunotolerant piglets
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CSF infection during the first of half of pregnancy can lead to abortion
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The shedding of CSFV begins 1-2 days after the appearance of clinical signs T The domestic swine population of most European countries are free from CSF T Classical swine fever causes oronasal infection T Classical swine fever can be transmitted by mating T CSF can cause transplacental infections T CSFV may case reproductive disorders T Classical swine fever targets lymphatic tissues T CSF infections result in thrombocytopenia T Clinical signs of Classical Swine fever are mainly seen in 6-12 week old piglets in vaccinated herds T Classical swine fever infection during the first half of pregnancy can lead to abortion T Wild boars play the main role in the maintenance of CSF virus in endemic areas T Wild boar may play a role in the maintenance and spread of CSFV
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94
In acute Classical swine fever skin haemorrhages and bloody nasal discharge can be observed
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95
Normal sized spleen can be observed in uncomplicated cases of subacute Classical swine fever
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Classical swine fever infection results in immunosuppression
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Central nervous signs might be seen in classical swine fever
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98
Porcine circovirus 2 may cause lesions similar to Classical Swine Fever
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99
Low virulence strains of CSFV may cause reproductive problems
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100
CSFV may damage the lymphatic tissues and blood vessel endothelial cells
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101
Swine can shed CSFV in the incubation period
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102
Skin suffusions and haemorrhages are signs of Classical Swine Fever
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Contaminated pork meat can play a role in the transmission of CSFV
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Attenuated vaccines are developed for immunization of swine against CSFV
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The Classical Swine Fever may appear in a milder form in wild boar than in domestic swine
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Acute classical swine fever can cause haemorrhagic pneumonia
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Classical swine fever virus can cause immunotolerance in swine
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108
Classical swine fever virus causes lympho-histiocytic encephalitis in pigs
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Low virulence strains of CSFV may lead to asymptomatic infection
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110
CSF is spread via infected pigs
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Sows infected by CSF will have immunotolerant piglets
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CSF can hardly be distinguished from African swine fever
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Incubation of CSF is 8-22 days
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CSF was first written about in USA
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CSF virus has good resistance
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CSF is frequently complicated with bacterial infections
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The clinical signs of CSF and ASF are similar
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Serological cross reactions my occur between BVD virus and CSFV
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Only domestic swine and wild boars are susceptible
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120
Fever, anorexia haemorrhages in the skin and weakness of the hind legs are the most important sign
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The CSFV typically damages endothelial- and lymphatic tissue
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Classical swine fever is a notifiable disease in Europe
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In subacute CSF we can observe signs of pneumonia during necropsies
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