Fitz - Pharm Of RA Flashcards by Erin Kretovics | Brainscape

Q

Reponse to MTX takes

A

25-30 wks

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Q

Toxicity of MTX

A

Hepatotoxicity, pulmonary damage

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Q

All ppl on MTX should get

A

follic acid, 1mg daily

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Q

Represses NF-kappaB transcription

A

Anti-inflammaotr glucocorticoids

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Q

Soluble TNF receptor

A

Entanercept

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Q

Anti-TNF monoclonal Abs

A

Infliximab, adalimumab

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Q

Anti-TNFalpha agents increase the risk of

A

Serious infections - esp TB

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Q

Oral JAK inhibitor

A

Tofacitinib

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Q

DMARD of choice for mild to moderate RA

A

Low-dose MTX

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