Fish & Invertebrate Nephrology & Urology

Question 1

Describe nephrocalcinosis in fish.

What species is particularly susceptible?

What environmental parameters is this associated with?

What lesions are typically found at necropsy?

Answer 1

Nephrocalcinosis.

• Rainbow trout production.
• Associated with high CO2 levels, also dietary manganese deficiency and selenium, arsenic toxicity.
• Lesions – hard, off-white renal nodules.
• Histo – tubular accumulations of mineral without apparent epithelial cell damage, granulomatous inflammation, fibrosis