firts chapter Flashcards

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1
Q

ways that drug enter the body.

A
  • Oral administration
  • Absorbtion through the skin or other membranes
  • Inhalation
  • Injection
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2
Q

oral administration

A

Via Mouth Nature of GI tract

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3
Q

Easiest method
• Provides a degree of safety (taste, vomit)
• Slow absorption are through?

A

Via Mouth

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4
Q
Prevents some absorption
• pH value of drug (weakly acidic is better absorbed)
• Alcohol neutral—easily absorbed
• Substances must be lipid-soluble
• Pass to liver (first-pass metabolism)
• Drugs given at elevated doses Are?
A

the nature of GI Tract

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5
Q

ways of injection.

A

Intravenous injection, Intramuscular, Subcutaneous.

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6
Q

INHALATION

A

gas or vapor state, Delivery.

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7
Q

ABSORPTION THROUGH THE SKIN OR MEMBRANES.

A

Intranasal, Through mouth, Suppository, Transdermal patch,

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8
Q

HOW DO DRUGS EXIT THE BODY?

A

elimination, Metabolic events, Chemical properties

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9
Q

FACTORS DETERMINING THE BEHAVIORAL IMPACT OF DRUGS.

A

Timing

  1. Drug Interactions (Drug x Drug)
  2. Cross-Tolerance and Cross-Dependence
  3. Individual Differences
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10
Q

the common characteristic of timing.

A

Latency period
• Increase of effect
• Maximum of effect
• Extended-release doses

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11
Q

process of changing the molecular structure of a drug into a form that
is more easily removed by the body

A

Biotransformation

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12
Q

Acute effect of one drug diminished when taken with

another

A

Antagonistic

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13
Q

INDIVIDUAL DIFFERENCES

A
  • Weight
  • Gender
  • Ethnicity
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14
Q

Tolerance for another drug from taking of one drug

A

Cross-tolerance

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15
Q

One drug substitute for another

A

Cross-dependence

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