First Week of Development Flashcards

1
Q

Where does fertilization occur?

A

the ampulla of the uterine tube

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2
Q

When can a sperm fertilize an egg?

A

only after undergoing capacitation and acrosome reaction

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3
Q

Capacitation

A

period of conditioning that takes place in female reproductive tract lasting 7 hours

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4
Q

Acrosome reaction

A

induced by zona proteins after the sperm binds to the zona pellucida, this process releases enzymes that allow the sperm to penetrate the zona pellucida

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5
Q

How many phases does fertilization have?

A

6 phases

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6
Q

Phase 1 of fertilization

A

passage of sperm through the corona radiate of the oocyte

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7
Q

Phase 2 of fertilization

A

penetration of the zona pellucida, the release of acrosomal enzymes allows the sperm to penetrate the zona pellucida and come in contact with the plasma membrane of the oocyte

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8
Q

Phase 3 of fertilization

A

fusion of the plasma cell membranes of the oocyte and sperm, sperm head and tail enter the oocyte

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9
Q

Phase 4 of fertilization

A

completion of the second meiotic division of the oocyte- forms the female pronucleus and the second polar body

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10
Q

Phase 5 of fertilization

A

formation of the male pronucleus- the tail degenerates and the nucleus of the sperm enlarges, DNA replication occurs

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11
Q

Phase 6 of fertilization

A

breakdown of the pronuclear membranes and restoration of diploid number of chromosomes

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12
Q

Cleavage

A

division of the zygote begins approx. 30 hours after fertilization

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13
Q

What are the cells that become smaller during mitotic division of the zygote called?

A

balstomeres

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14
Q

Morula

A

the 16 to 32 cell stage

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15
Q

Blastocyst formation

A

around day 4 the morula enters the uterus, uterine fluid penetrates through the zona pellucida to the intercelluar space of the inner cell mass, the fluid filled space is called the blastocystic cavity

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16
Q

Blastomeres are seperated into two parts

A

Inner cell mass is the embroblast that gives rise to the embryo proper, and the outer cell mass or tropoblast that forms the placenta

17
Q

When does implantation occur?

A

6 days after fertilization