Third Week of Development Flashcards

1
Q

Gastrulation

A

process of establishing 3 germ layers and begins with the formation of the primitive streak

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2
Q

Cells of the epiblast migrate towards to the primitive streak, detach, and slip underneath the epiblast in a process called what?

A

invagination

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3
Q

Mesenchymal cells migrate cranially from the primitive node and pit forming a median celluar cord called what?

A

the notochordal process, this process aquires a lumen known as the notochordal canal

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4
Q

The prechordal plate will be important in the develpment of the _____ while the notochord will be the basis for the formation of the parts of the ____________________.

A

forebrain, axial skeleton and spinal cord

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5
Q

What does the cloacal membrane form?

A

the anus

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6
Q

When are body axes formed?

A

before and during the time of gastrulation

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7
Q

When does the primitive streak regress?

A

the end of the fourth week

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8
Q

The beginning of the 3rd week of development (gastrulation) is a highly sensitive period for what?

A

teratogenesis and malformations

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9
Q

Holoprosencephaly

A

high doses of alcohol at the gastrulation stage kills cells in the anterior midline of the germ disc producing a deficiency of the midline in craniofacial structures, fore brain is small

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10
Q

Sirenomelia

A

insufficient mesoderm formed in the caudal most region of the embryo , abnormalities in the lower half of body, absent of fused lower limbs (sometimes associated with maternal diabetes)

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11
Q

Situs inversus

A

left and right organ positions are reversed

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12
Q

Sacrococcygeal teratoma TEST QUESTION

A

proliferation of remnants of the primitive streak, forms tumors in all 3 germ layers, most common tumor in newborns

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