First test Flashcards
Evolution, classification
Theory of Evolution
The theory that all species developed from earlier forms by the accumulation of genetic changes over many successive generations. The change in genetic frequency in a population over time
Gene Pool
The genetic constitution of an entire population of a given species
Natural Selection
The mechanism proposed by Darwin as the way that evolutionary change takes place. The environment selects the change.
The four premises of natural selection
Overproduction, variation, limits on population growth, differential reproductive success
overproduction
Each species has the capacity to produce more offspring than will survive to maturity.
Variation
The individuals in a population exhibit variation in their traits.
Limits on population growth or struggle for existence.
There is only so much food, water, light, growing space, available, and organisms compete with one another for limited resources. Not all individuals will survive to reproductive age.
Differential reproductive success
“Survival of the fittest” - the individuals that possess the most favorable combination of characteristics are most likely to survive and reproduce, passing their traits on to the next generation
Three main points of Darwin’s evolution
Natural selection acts on existing variation.
Those with the best combination of traits reproduced best.
Linnaean branched tree of identification reflects common ancestry.
Interaction of natural selection, variation, and adaptation is based on these three inferences
- Reproductive effort produces more individuals than the environment can support.
- Statistically those with the best traits leave more offspring
- Leads to gradual changes in the proportion of traits in a population.
True of False: Variation necessary for evolution by natural selection must be heritable
True. They must be able to be passed on to offspring
If evolution is dependent on inheritance, do individuals evolve?
No. Natural selection acts on individuals by determining which of them will survive to reproduce, but individuals do not evolve in their lifetimes. Populations evolve over may generations.
Seven evidences for evolution
a. artificial selection
b. natural selection
c. homologies
d. biogeography
e. fossil record
f. convergent evolution (analogies)
g. genetics
artificial selection
The selecting agent is humans. Example: breeders developing many varieties of domestic plants and animals in just a few generations (airedales and collies from wolves, brussel sprouts from cabbage)
Homologies
Features in different species that are similar in underlying structure due to a common evolutionary origin (homologous structures) Ex: bird wing, bat wing, dolphin flipper, human arm.
Analogies
Analogous structures - not homologous but have similar functions. Ex: Bird wings and insect wings (no underlying structure like bones in the insect wing - it is an outgrowth of their external wall)
Why do analogies demonstrate evolution?
Because they demonstrate Convergent Evolution - that populations with separate ancestries may adapt in similar ways to similar environmental demands.
Biogeography
The study of the distribution of plants and animals. Basic tenet is that each species originated (evolved) only once.
Why does biogeography support evolution?
If evolution were not a factor in distribution, we would expect to find a given species everywhere that it could survive. Africa and Brazil have similar climates, but different animals (no elephants in Brazil) because they originated in one place and couldn’t cross the barrier of the ocean. Darwin’s finches.
Why does the fossil record support evolution
Provides a record of animals and plants that lived earlier and when and where they lived. Lines of descent (evolutionary relationships) can be inferred. Sometimes they provide direct evidence of the origin of the new species from preexisting species. (example - precursor to whale evolution was a 4-legged land animal)
vestigial structures
Land animal to whale, didn’t need hips anymore, but tiny non-functional bones left in place in the whale. Human example: wisdom teeth. Remnants of more developed organs that were present in ancestral organisms
Why does genetics support evolution
The genetic code is universal - evidence that organisms arose from a common ancestor. example: “AAA” codes for phenylalanine in all organisms examined to date..
Phylogenetic tree
A diagram showing lines of descent, can be derived from differences in the amino acid sequence of a common protein like cytochrome c, or in nucleic acid sequences of DNA. Closely related species branch closely, unrelated branch further away.
Background for the formation of Darwin’s views
- HMS Beagle 1831-1835 Spent months on the Galapagos islands and South America (went around the world)
- Noticed Temperate species in South America were not like those in Europe and island species were like those on the nearby continents.
- Suggested that species could arise from ancestral forms.
- Published Origin of Species by Means of Natural Selection in 1859 (took him 20 years!)
Scientist working at the same time as Darwin, independently came up with the conclusion that evolution occurs by natural selection.
Alfred Russel Wallace - worked in Indonesia
Adaptation
Evolutionary modification that improves the chances of survival and reproductive success.
3 Definitions of Darwinian Evolution
- A change in genetic frequency in a population of organisms through time.
- The diversification of biological life from the advent of the earliest microbes to modern life forms.
- A natural process that provides sufficient explanation for all natural phenomena without having to appeal to purpose or design.
5 Reasons for change in genetic frequency according to Darwin’s evolution
- Natural Selection
- Genetic Drift
- Emigration/immigration
- Founder’s effect
- Sexual Selection
Founder’s effect
The genetic drift that results when a small number of individuals from a large population colonize a new area.
(like birds flying to a new area), they bring only a fraction of the genetic variation present in the original population.
Genetic Drift
The production of random evolutionary changes in small breeding populations. one allele may be eliminated by chance. Decreases genetic variation within a population, increases genetic differences among different populations.
Emmigration/Immigration
Migration of breeding individuals between populations causes a corresponding movement of alleles, or gene flow. Counteracts the effect of natural selection and genetic drift. Reduces the amount of variation between two populations
Sexual selection
A special case of natural selection.
An organism’s ability to obtain a mate (at any cost!). Peacocks tails, fighting seals, dancing fruit flies. Features can be harmful to the individual’s survival (peacock tails can also attract predators). Irish Elk antlers
Critics of the abiogenesis theory - life from non-life (Evolution Definition #2)
Francis Crick - Discovered DNA - DNA too complex to have arisen from any reasonably known or postulated condition on earth. Suggested a seeding event (from outer space).
Craig Venter - sequenced the human genome - Life occurs everywhere throughout the universe. Life on our planet most likely is the resultof a panspermic event (seeding from outer space). Need the right tools to prove life happens.
Christian criticism of abiogenesis
Lack of compelling de-randomizing mechanism. Life must be organized from intelligent design if we accept that there is a creator.
If evolution from nonlife, doesn’t it require a world changing at a speed conducive for evolution? (how could one event have sparked it and then everything slowed - inconsistent).
Embracing a naturalistic explanation for life’s origins advanced by philosophical materialists who often used the theory to support antitheistic philosophies.
7 groups who endorsed the 3rd definition of Darwin’s evolution (natural process without needing purpose or design)
- Marxists
- Eugenics movements and Nazism
- Freud
- Scientific Materialism (Naturalism)
- Situational ethicists
- Deweyan educational philosophy
- Others
Historical context of the rise of evolutionary theory
Before 1850s Christian explanations pervaded science and origin of life.
Many believed in the immutability of species.
Some Christians had ideas: Augustine (God is unchangeable, so he must create from nothing, not from himself), Linnaeus, conservative theologians BB Warfield, CHarles Hodge (“if God creates, it matters not how he creates”)
Immutability of species
Each individual species on the planet was specially created by God and could never fundamentally change. What supports it:
- catastrophism - earth’s geology created by big events like volcanos or floods (Noah’s) - these caused extinction of some species.
- orderly universe created by God
- Ussher’s Chronology- literal interpretation of the old testament - young earth 4000 BC
Natural Theology
Before Darwin, in Paley’s book, influenced him
- Saw scientific theory as a way to think God’s thoughts after him
- was a perspective that attempted to understand God’s purpose by examining natural features
- many embraced catastrophism, but then uniformitarianism
- generated a debate on age of earth
Mistakes in NT thinking that confused theory and truth
- God’s purposes for creation could be learned thru study of nature
- Catastrophism was raised to dogma
- Immutability of species
What did NTs believe?
That they could prove the existence of God and describe him using nature alone, without the scriptures or miracles. The perfection of an organism adaptation to the environment was proof that God designed all life.
Uniformitarianism
Lyell - the mountains, valleys, and other features were not created in their present forms, but were formed slowly over long periods of time, so the earth is old. “Principles of Geology” Darwin took a copy onthe Beagle
Jean Baptist Lamarck
put fossils in evolutionary sequence. Believed that the long neck of the girffe developed when short-necked ancestors ate leaves instead of grass. Offspring inherited the neck and stretched it longer.(inner drive for self improvement)
Gradualism
The slow and gradual changes that happen within an organism or society to make a better environmental fit . An example of gradualism is the stripes of a tiger developing over time so they are better able to hide in tall grass.
Modern synthesis
combined theory of natural selection with concepts of modern genetics and inheritance (Neo-Darwinian Synthesis)
Mendel
Father of genetics. 1860s but work was rediscovered in 20th century.
fixed alleles
An allele that is the only variant that exists for that gene in all the population. A fixed allele is homozygous for all members of the population. The term allele normally refers to one variant gene out of several possible for a particular locus in the DNA
Hardy Weinberg Theorem
Allelic frequencies do not change in a population of random mating individuals
- segregation and recombination do not alter genetic frequencies
- allelic ratios (producing phenotypic ratios) do not equal genotypic ratios.
- evolution must be acting on a population because allele frequencies in nature are often significantly different from what the HW principle would predict.
What does Hardy Weinberg show
- That low frequencies of heterozygotes produce rare homozygous recessive (hard to lose alleles that are lethal recessive).
- Hereditary mechanisms by themselves do not alter genetic frequencies.
5 assumptions required for a population at Hardy Weinberg Equilibrium
- Infinite population size - it is a statistical tool, so needs a large population so that the effect of chance is small. Allele frequency in a small population are more likely to be affected by chance events
- No migration - no exchange of genes with other populations that might have different allele frequencies (no migration in or out)
- No net mutations - the relative numbers of B and b must not change due to mutations
- Random mating - no selection of mates based on the genotype. equal probabilities of matings among genotypes
- No natural selection - if it occurs, certain genotypes are favored over others. Consequently the allele frequencies will change and the population will evolve.
What is the impact that nearly all populations show some change from H-W
They are evolving. Two main causes:
natural selection
genetic drift
other causes
What natural selection acts on
- variation within populations
2. variation between populations
Variation within populations
a. quantitative characters
b. polymorphic traits
c. ways to measure genetic diversity (%heterozygotes vs. # of different nucleotides in a base pair sequence, distribution of genes on different chromosomes)
Origins of genetic variation
- Mutation
2. Recombination of traits due to sexual reproduction
Mutation types
- point mutations (silent, each person has some, a change in one base pair)
- gene or chromosomal duplication (chromosomes duplicate)
- nondisjunctions (when one chromosome doesn’t split it’s pair properly, resulting in an unequal distribution of chromosomes
- inversion -chromosome segment flips
- translocation - chromosome segment reattaches to another chromosome (bison and cattle 2n=60, sterile)
- chromosomal fusion 2n-46 (human), 2n-48 (chimp) because human chromosome #2 fused, so we have less than apes.
Maintainers of genetic variation
- diploidy
- heterozygotic advantage
- frequency dependent selection
- neutral variation
Diploidy
a state of being diploid, that is having two sets of the chromosomes (and therefore two copies of genes), especially in somatic cells
Heterozygote advantage
the heterozygous genotype has a higher relative fitness than either the homozygous dominant or homozygous recessive genotype (example: sickle cell anaemia)
Frequency dependent selection
evolutionary process by which the fitness of a phenotype depends on its frequency relative to other phenotypes in a given population.
- In positive frequency-dependent selection, the fitness of a phenotype increases as it becomes more common.
- In negative frequency-dependent selection, the fitness of a phenotype decreases as it becomes more common
Neutral variation
differences in DNA sequence that do not confer a selective advantage or disadvantage; recessive alleles in diploid eukaryotes. balancing selection. occurs when natural selection maintains two or more forms in a population
How Natural selection works: 2 ways
- Phenotype variation
2. Maintains sexual reproduction in the face of disadvantages of sexual reproduction
Directional selection
bell curve shifts to one side - environmental changes favor the selection of more suitable phenotypes, causing the distribution to shift - peppered moths are an example
Diversifying selection
From a bell curve to a curve that looks like two humped camel - environmental changes favor the selection of more suitable phenotypes at both extremes of the normal distribution, causing a split. - example is the finches on the Galapagos is an example -limited food supply favored wide beaks that could strip off bark to get insects and long beaks to open cactus fruits (two extremes)
Stabilizing selection
bell curve gets narrower - in a stable environment stresses tend to weed out unsuitable phenotypes, making the population more uniform
3 types of Phenotype variation
- Directional selection
- Diversifying Selection
- Stabilizing selection
Advantages and disadvantages of sexual reproduction
Advantages: More variation assists with survival. It increases the chance that at least some offspring of a parent survive. Example: if a deadly infection occurs in the population. Greater variety increases the chance that some of the population will survive.
Disadvantages: Requires two parents. So a population of animals reproducing sexually would produce only half as many offspring as a population reproducing asexually, such as starfish do.
Leks
Related to sexual selection - an aggregation of male animals gathered to engage in competitive displays, lekking, to entice visiting females which are surveying prospective partners. Birds of paradise, turkeys, etc.
Practical Application of Evolutionary Theory
- Production of new (RNA) molecules in lab to expedite the evolution of metabolite microbes. (CRISPR, used in gene therapy)
- agricultural benefits associated with avoidance of pesticide resistance (roundup ready crops)
- Understanding antibiotic resistance -
Problem of developing medical ethics based on evolutionary theory
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True or false? Mutations determine the direction of evolutionary change
False. The occurrence of mutations is random. Natural selection can help retain and increase the proportions of individuals with beneficial mutations in a population (or reduce or eliminate those with harmful ones), but nothing but chance influences the initial mutation.