First Exam Semester 2 Flashcards
Selective Serotonin Reuptake Inhibitors (SSRIs)
Fluoxetine (Prozac)
Paroxetine (Paxil)
Sertraline (Zoloft)
Fluvoxamine (Luvox)
Citalopram (Celexa)
Escitalopram (Lexapro)
Selective Serotonin Reuptake Inhibitors (SSRIs) and 5-HTReceptor Modulators
Vilazodone (Viibryd)
Vortioxetine (Trintellix)
Trazodone
Nefazodone
Mirtazipine
Serotonin (5-HT) and Norepinephrine (NE) Reuptake Inhibitors (SNRIs)
Venlafaxine (Effexor)
Desvenlafaxine (Pristiq)
Duloxetine (Cymbalta)
Levomilnacipran (Fetzima)
Buproprion (Wellbutrin)
(not a SNRI Dopa and NE reuptake inhibitor)
TCAs
Im/Clom/Des-ipramine
Ami/Nor-tryptyline
Other Antidepressants
Selegiline/EMSAM Patch
Ketamine
SSRI’s ADRs
ADR-s all except SD gone within a few weeks
5HT4- Diarrhea
5HT3- NV
5HT2- Solmnolence and Sexual Dysfunction
5HT1-Headache
SSRI other negative Effects.
Weight gain due to 5-HTc antagonism - Paroxetine
Triptans
Sumatriptan
Naratriptan
Razatriptam
Zolmitriptan
Almotriptan
Eletriptan
Frovatriptan
What are the GABA A subtypes?
a 1-6
b 1-3
d
e
g 1-3
q
p
p 1-3 (GABA C)
What are the GABA B subtypes?
1
2
GABA receptor subtypes and effects
GABA A
a1 - (Z drug Target) Sedative / Hypnotic, reinforcing
a2 and 3 - Anxiolytic, anticonvulsant (a2)
a5 - Leaning and memory (Psuedoalzhiemers with extended use)
b3 - Respiratory Drive, hypnotic
GABA B
Muscle relaxant
Z drugs
GABA A a1 subunit
Zolpidem
Zaleplon
Eszoplicone (Least Specific)
Benzodiazepines (BZD)
Triazolam
Clonazepam
Alprazolam
Lorazepam
Diazepam
Oxazepam
Chlordiazepoxide
The Clear And Least Desirable Option, Chlordiazepoxide
Typical Anti-Psychotics
Droperidol
Pimozide
Loxapine
Molindone
Thiothixene
Chlorpromazine
Fluphenazine
Haloperidol
Damnit People Let Me Thoroughly Cry For Help
Atypical Anti-Psychotics
Latuda
Vraylar
Quetiapine
Paliperidone
Risperidone
Olanzapine
Fanapt
Clozapine
Ziprasidone
Aripiprazole
Rexulti
Saphris
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