First Aid Substance Related Disorders II Flashcards

1
Q

how does PCP work

A

antagonizes NMDA glutamate R and activates DA neurons

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2
Q

Sx of PCPC

A
rage
erythema
dilated pupils
delusions
amnesia
nystagmus
excitation
skin dryness
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3
Q

rotatory nystagmus

A

PCP

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4
Q

Tx of PCP intoxication

A

monitor vitals temp and electrolytes and minimize sensory stimulation
benzos for agitation anxiety, muscle spasms and seizures
antipsychotics for agitation or psychotic Sx

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5
Q

flashbacks with PCP

A

recurrence of intoxication Sx from release of drug in body lipid stores during wtihdrawal

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6
Q

Sx of intoxication of sedatives/hypnotics

A

drowsiness, confusion, hypotension, slurred speech, incoordination, ataxia, mood lability, impaired judgement, nystagmus, respiratory depression and coma or death in overdose

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7
Q

treatment for sedative intoxication

A

maintaining ABCs and monitor vital sounds

activated charcoal and gastric lavage

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8
Q

Tx for benzo OD

A

flumazenil

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9
Q

T for barbituate intoxication

A

alkalinize urine with sodium bicarb to promote renal excretion

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10
Q

beware of what with use of flumazenil

A

seizures

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11
Q

what is Tx of choice for opiate OD

A

naloxone

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12
Q

withdrawal Sx of benzo or barb dependence

A

life threatening can lead to generalized tonic clonic seizures

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13
Q

Tx sedative hypnotic withdrawal

A

benzo taper

carbamazepine or valproic acid taper for seizure precaution.

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14
Q

signs of opiate intoxication

A

nausea, vomiting, sedation, decreased pain perceptions, decreased GI motility, pupil constriction
respiratory depression

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15
Q

signs of opioid intoxication

A

drowsiness, nausea/vomiting, constipation, slurred speech, constricted pupils, seizures and respiratory depression which may progress to coma or death in overdose

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16
Q

serotonin syndrome

A

hyperthermia, confusion, hyper or hypo tension and muscular rigidity

17
Q

treatment of opioid intoication

A

ABCs

give naltrexone or naloxone in OD

18
Q

triad of opioid OD

A

respiratory depression
altered mental status
miosis

19
Q

Treatment for opioid withdrawal

A

clonidine
NSAIDs
dicyclomine for abdominal cramps

20
Q

COWS

A

clinical opioid withdrawal scale

21
Q

what are the hallucinogenic drugs

A

psilocybin (mushrooms), mescaline (peyote cactus) and LSD

22
Q

intoxication with hallucinogens

A

perceptual changes, labile, dilated pupils, tachycardia, hypertension, hyperthermia, tremors, incoordination, sweating and palpitations

23
Q

signs of intoxication with weed

A

euphoraia, anxiety impaired motor coordination, perceptual disturbances, mild tachy, anxiety, conjunctival injection, dry mouth and inc appetite

24
Q

withdrawal Sx weed

A

irritability, anxiety, restlessness, aggression, strange dreams, depression, Ha, sweating, insomnia, nausea, craving and dec appetite

25
how does caffeine work
adenosine antagonist causing inc in cAMP
26
greater than 1 g (8-12 cups) cause what Sx with caffeine
tinnitus, severe agitation, visual light flashes and cardiac arrythmias
27
withdrawal from caffeine
50-75% users | HA, fatigue, irritability, nausea, vomiting, drowsiness, anxiety, muscle pain and mild depression
28
effects of nicotine
restlessness, insomnia, anxiety and inc GI motility
29
withdrawal Sx of nicotine
intense craving, dysphoria, anxiety, poor concentration, dec heart rate, inc appetite, irritability, restlessness and insomnia
30
cigarrette smoking and pregnancy
low birth weight and persistent pulmonary HTN of newborn
31
varenicline
chantix | nAChR partial agonist
32
bupropion
zyban | partial agonist at nAChR and inhibitor of DA reuptake