First Aid Substance Related Disorders II Flashcards

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1
Q

how does PCP work

A

antagonizes NMDA glutamate R and activates DA neurons

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2
Q

Sx of PCPC

A
rage
erythema
dilated pupils
delusions
amnesia
nystagmus
excitation
skin dryness
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3
Q

rotatory nystagmus

A

PCP

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4
Q

Tx of PCP intoxication

A

monitor vitals temp and electrolytes and minimize sensory stimulation
benzos for agitation anxiety, muscle spasms and seizures
antipsychotics for agitation or psychotic Sx

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5
Q

flashbacks with PCP

A

recurrence of intoxication Sx from release of drug in body lipid stores during wtihdrawal

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6
Q

Sx of intoxication of sedatives/hypnotics

A

drowsiness, confusion, hypotension, slurred speech, incoordination, ataxia, mood lability, impaired judgement, nystagmus, respiratory depression and coma or death in overdose

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7
Q

treatment for sedative intoxication

A

maintaining ABCs and monitor vital sounds

activated charcoal and gastric lavage

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8
Q

Tx for benzo OD

A

flumazenil

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9
Q

T for barbituate intoxication

A

alkalinize urine with sodium bicarb to promote renal excretion

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10
Q

beware of what with use of flumazenil

A

seizures

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11
Q

what is Tx of choice for opiate OD

A

naloxone

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12
Q

withdrawal Sx of benzo or barb dependence

A

life threatening can lead to generalized tonic clonic seizures

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13
Q

Tx sedative hypnotic withdrawal

A

benzo taper

carbamazepine or valproic acid taper for seizure precaution.

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14
Q

signs of opiate intoxication

A

nausea, vomiting, sedation, decreased pain perceptions, decreased GI motility, pupil constriction
respiratory depression

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15
Q

signs of opioid intoxication

A

drowsiness, nausea/vomiting, constipation, slurred speech, constricted pupils, seizures and respiratory depression which may progress to coma or death in overdose

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16
Q

serotonin syndrome

A

hyperthermia, confusion, hyper or hypo tension and muscular rigidity

17
Q

treatment of opioid intoication

A

ABCs

give naltrexone or naloxone in OD

18
Q

triad of opioid OD

A

respiratory depression
altered mental status
miosis

19
Q

Treatment for opioid withdrawal

A

clonidine
NSAIDs
dicyclomine for abdominal cramps

20
Q

COWS

A

clinical opioid withdrawal scale

21
Q

what are the hallucinogenic drugs

A

psilocybin (mushrooms), mescaline (peyote cactus) and LSD

22
Q

intoxication with hallucinogens

A

perceptual changes, labile, dilated pupils, tachycardia, hypertension, hyperthermia, tremors, incoordination, sweating and palpitations

23
Q

signs of intoxication with weed

A

euphoraia, anxiety impaired motor coordination, perceptual disturbances, mild tachy, anxiety, conjunctival injection, dry mouth and inc appetite

24
Q

withdrawal Sx weed

A

irritability, anxiety, restlessness, aggression, strange dreams, depression, Ha, sweating, insomnia, nausea, craving and dec appetite

25
Q

how does caffeine work

A

adenosine antagonist causing inc in cAMP

26
Q

greater than 1 g (8-12 cups) cause what Sx with caffeine

A

tinnitus, severe agitation, visual light flashes and cardiac arrythmias

27
Q

withdrawal from caffeine

A

50-75% users

HA, fatigue, irritability, nausea, vomiting, drowsiness, anxiety, muscle pain and mild depression

28
Q

effects of nicotine

A

restlessness, insomnia, anxiety and inc GI motility

29
Q

withdrawal Sx of nicotine

A

intense craving, dysphoria, anxiety, poor concentration, dec heart rate, inc appetite, irritability, restlessness and insomnia

30
Q

cigarrette smoking and pregnancy

A

low birth weight and persistent pulmonary HTN of newborn

31
Q

varenicline

A

chantix

nAChR partial agonist

32
Q

bupropion

A

zyban

partial agonist at nAChR and inhibitor of DA reuptake