finals study Flashcards
Testing of the last wash in the eluate procedure ensures that:
a) The check cells will work
b) The antibody identified in the eluate is the antibody attached to the red cells
c) The antibody identified in the eluate should be in the patient plasma
d) The pH of the eluate is appropriate for panel cell testing
b) The antibody identified in the eluate is the antibody attached to the red cells
Other than anti-IgG, what is in Polyspecific AHG reagent?
a) IgM
b) C9
c) C3d
d) C4
c) C3d
Which statement is true for allo-adsorption procedure?
a) It is utilized when patients have been recently transfused
b) It removes antibody from patient cells
c) QC for this procedure involves testing of the last wash
d) Patient cells are used to remove autoantibody from their own plasma
a) It is utilized when patients have been recently transfused
What test should be done next
with the following results:
Anti-A: 4+
Anti-B: 0
Anti-D: 0
A1 cell: 3+
B cell: 3+
SC1- IS: 3+ 37C: 3+ AHG: 0 CC: 2+
SC2- IS: 3+ 37C: 1+ AHG: 0 CC: 2+
Auto- IS: 3+ 37C: 3+ AHG: 3+ CC: NT
a) Adsorption
b) Phenotype for M antigen
c) DAT
d) Anemia Studies
c) DAT
Which DAT results indicate that an
elution should be performed?
a) AHG + IgG+ C3d-
b) AHG – IgG– C3d-
c) AHG + IgG- C3d+
d) AHG + IgG- C3d-
a) AHG + IgG+ C3d-
Which test result differentiates between high incident antibody and autoantibody workup?
a) Elution
b) Auto Control
c) Adsorption
d) DAT
b) Auto Control
Shortness of breath indicates hemolytic anemia, what test differentiates between cold acting antibodies and warm acting antibodies being the cause?
a) Auto control
b) Cold Screen
c) Elution
d) Donath Landsteiner
b) Cold Screen
Which type of anemia is NOT often associated with compliment activation?
a) PCH
b) CAD
c) Drug Adsorption
d) WAIHA
c) Drug Adsorption
Which antibody is most likely acting in this cold screen:
SC1- IS: 3+ 37C: 2+ AHG: 0 CC: 2+
SC2- IS: 3+ 37C: 2+ AHG: 0 CC: 2+
SC3- IS: 3+ 37C: 2+ AHG: 0 CC: 2+
Cord Cell- IS: 3+ 37C: 2+ AHG: 0 CC: 2+
a) Anti-I
b) Anti-IH
c) Anti-i
d) Anti-M
b) Anti-IH
What test helps to differentiate pathologic vs benign CAD?
a) Antibody ID
b) DAT
c) Antibody Titer
d) Donath Landsteiner
c) Antibody Titer
Which of the following is NOT a control for the Donath Landsteiner test?
a) Patient cells + normal plasma
b) Samples kept at 37C until testing commences
c) Normal plasma + patient plasma
d) Normal plasma
a) Patient cells + normal plasma
Which of the following diagnoses is NOT reasonable for the following serological results:
Anti-A: 4+
Anti-B: 0
Anti-D: 0
A1 cell: 0
B cell: 3+
SC1- IS: 0 37C: 1+ AHG: 3+ CC: NT
SC2- IS: 0 37C: 1+ AHG: 3+ CC: NT
Auto- IS: 3+ 37C: 3+ AHG: 3+ CC: NT
a) WAIHA
b) CAD
c) Aldomet Antibody
d) Transfusion reaction with anti-e
b) CAD
This mechanism of drug related hemolysis is less severe with penicillin and most severe with Cefotetan. Which mechanism is it?
a) Drug Adsorption
b) Immune Complex
c) Membrane Modification
d) Drug-Independent Auto Antibody
a) Drug Adsorption
Which transfusion recommendation is appropriately matched to its autoantibody diagnosis?
a) Darzalex – don’t transfuse
b) WAIHA – transfuse with blood warmer
c) CAD – wash the cells
d) Cefotetan – transfuse as normal
d) Cefotetan – transfuse as normal
A crossmatch sample collected at 1405 on Monday would expire on which day at midnight?
a) Tuesday
b) Wednesday
c) Thursday
d) Friday
c) Thursday
When should a transfusionist be checking vitals?
a) Before the unit is started
b) 15 minutes after unit is started
c) 15 minutes after unit is completed
d) Both a and b
d) Both a and b
What blood type donor units should anti-A,B be used on?
a) A neg
b) B pos
c) AB pos
d) O neg
d) O neg