FINALS: BIOSAFETY & BIOSECURITY Flashcards
Become the code of practice for biosafety-the discipline addressing the safe handling and containment of infectious microorganisms and hazardous biological materials.
Biosafety in Microbiological and Biomedical Laboratories (BMBL)
Laboratory Biorisk Management Standard, the first internationally recognized management standard to specifically address hazards associated with microbiological laboratories at all containment levels
CWA-15793:2008
Containment principles, technologies, and practices implemented to prevent unintentional exposure to pathogens and toxins, or their unintentional release.
laboratory biosafety
Protection, control and accountability for valuable biological materials within laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release
laboratory biosecurity
protecting people from dangerous pathogens
biosafety
protecting pathogens from bad people
biosecurity
protecting pathogens from bad people
biorisk
BIOSAFETY + BIOSECURITY = ?
BIORISK
System or process to control safety and security risks associated with the handling or storage and disposal of biological agents and toxins in laboratories and facilities
Laboratory Biorisk Management
Process of identifying the hazards and evaluating the risks associated with biological agents and toxins, taking into account the adequacy of any existing controls, and deciding whether or not the risks are acceptable
Biorisk assessment
Actions and control measures that are put into place to reduce or eliminate the risks associated with biological agents and toxins
Biorisk Mitigation
Improving biorisk management by recording, measuring, and evaluating organizational actions and outcomes to reduce biorisk.
Biorisk performance
identify the specific hazard or threat, determine the consequences of an identified risk
risk assessment
identify all the existing controls and any additional ones that need to be applied
risk assessment
T or F
A laboratory biorisk assessment is an analytical procedure designed to characterize and evaluate safety and security risks in a laboratory.
True
T or F
A biorisk assessment allows a laboratory to determine the relative level of risk its different activities pose, and helps guide risk mitigation decisions so these are targeted to the most important risk.
True
what are all the risks: 5ps
Pathogen
Procedures
Personnel
PE
Place
an object that can cause harm
hazard
a person who has intent and/or ability to cause harm to other people, animals, or the institution
threat
can be based on either a hazard and/or a threat
risk
thelikelihoodofanundesirableeventhappening,that involves a specific hazard or threat and has consequences
risk
process of determining, subjectively, whether a risk is high or low, and whether it’s acceptable or not
risk evaluation
Suppose you are working with a seasonal influenza virus, conducting testing on a human respiratory specimen, on the bench-top, with no respiratory protection.
risk characteristics
Pathogenicity
Virulence
Host range
Communicability
Transmission
Environmental Stability
Agent properties
PPE
Training
SOPs
Equipment used
Procedures
• Eye protection
• Gloves
• Face shields
• Hair nets
• Ear plugs (when sonicating)
• Protective clothing (gowns)
• Footwear
• Respiratory Protection
PERSONAL PROTECTIVE EQUIPMENT (PPE)
Breaking the chain to manage the risk
Pathogen
Reservoir of pathogen
Portal of escape
Transmission
Route of entry/infectious dose Susceptible host
Points to consider
